Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications
Objective: To investigate the in vitro anti-elastase, anti-collagenase, and antimicrobial activities of the red pitaya peel extract for cosmetic application focusing on skin aging. Methods: Extraction was performed by the reflux method for 103 minutes at 56°C with 82% aqueous ethanol solution and t...
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| Format: | Article |
| Language: | English |
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Innovare Academic Sciences
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/60884/1/Anti-elastase%2C%20anti-collagenase%20and%20antimicrobial%20activities%20of%20the%20underutilized%20red%20pitaya%20peel%20an%20in-vitro%20study%20for%20anti-aging%20applications.pdf |
| _version_ | 1825932255472648192 |
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| author | Vijayakumar, Ramya Abd Gani, Siti Salwa Mohd Mokhtar, Nor Fadzillah |
| author_facet | Vijayakumar, Ramya Abd Gani, Siti Salwa Mohd Mokhtar, Nor Fadzillah |
| author_sort | Vijayakumar, Ramya |
| collection | UPM |
| description | Objective: To investigate the in vitro anti-elastase, anti-collagenase, and antimicrobial activities of the red pitaya peel extract for cosmetic application focusing on skin aging. Methods: Extraction was performed by the reflux method for 103 minutes at 56°C with 82% aqueous ethanol solution and the red pitaya peel extract was evaporated using a rotary evaporator. Anti-elastase and anti-collagenase properties were evaluated using the drug discovery kits (neutrophil elastase colorimetric and matrix metalloproteinase-1 colorimetric, respectively). The antimicrobial potential was analyzed using agar well diffusion method against 10 selected microorganisms, and the presence or absence of the inhibition zones was identified.
Results: The red pitaya peel extract exhibited remarkable inhibition percentage 87.62±0.05% and 96.92±0.02% for anti-elastase and anti-collagenase activities, respectively. Red pitaya peel extract showed significant inhibition against the Gram-positive Bacillus subtilis B29 with an inhibition zone diameter of 8.0±0.3 mm. Conclusion: The excellent anti-aging properties displayed by the underutilized red pitaya peel extract highlighted its potential as a natural source of anti-aging agent for cosmetic formulations. |
| first_indexed | 2024-03-06T09:39:10Z |
| format | Article |
| id | upm.eprints-60884 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:39:10Z |
| publishDate | 2017 |
| publisher | Innovare Academic Sciences |
| record_format | dspace |
| spelling | upm.eprints-608842019-04-29T07:49:59Z http://psasir.upm.edu.my/id/eprint/60884/ Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications Vijayakumar, Ramya Abd Gani, Siti Salwa Mohd Mokhtar, Nor Fadzillah Objective: To investigate the in vitro anti-elastase, anti-collagenase, and antimicrobial activities of the red pitaya peel extract for cosmetic application focusing on skin aging. Methods: Extraction was performed by the reflux method for 103 minutes at 56°C with 82% aqueous ethanol solution and the red pitaya peel extract was evaporated using a rotary evaporator. Anti-elastase and anti-collagenase properties were evaluated using the drug discovery kits (neutrophil elastase colorimetric and matrix metalloproteinase-1 colorimetric, respectively). The antimicrobial potential was analyzed using agar well diffusion method against 10 selected microorganisms, and the presence or absence of the inhibition zones was identified. Results: The red pitaya peel extract exhibited remarkable inhibition percentage 87.62±0.05% and 96.92±0.02% for anti-elastase and anti-collagenase activities, respectively. Red pitaya peel extract showed significant inhibition against the Gram-positive Bacillus subtilis B29 with an inhibition zone diameter of 8.0±0.3 mm. Conclusion: The excellent anti-aging properties displayed by the underutilized red pitaya peel extract highlighted its potential as a natural source of anti-aging agent for cosmetic formulations. Innovare Academic Sciences 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60884/1/Anti-elastase%2C%20anti-collagenase%20and%20antimicrobial%20activities%20of%20the%20underutilized%20red%20pitaya%20peel%20an%20in-vitro%20study%20for%20anti-aging%20applications.pdf Vijayakumar, Ramya and Abd Gani, Siti Salwa and Mohd Mokhtar, Nor Fadzillah (2017) Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications. Asian Journal of Pharmaceutical and Clinical Research, 10 (8). 251 - 255. ISSN 0974-2441; ESSN: 2455-3891 https://innovareacademics.in/journals/index.php/ajpcr/article/view/19048 10.22159/ajpcr.2017.v10i8.19048 |
| spellingShingle | Vijayakumar, Ramya Abd Gani, Siti Salwa Mohd Mokhtar, Nor Fadzillah Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title | Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title_full | Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title_fullStr | Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title_full_unstemmed | Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title_short | Anti-elastase, anti-collagenase and antimicrobial activities of the underutilized red pitaya peel: an in-vitro study for anti-aging applications |
| title_sort | anti elastase anti collagenase and antimicrobial activities of the underutilized red pitaya peel an in vitro study for anti aging applications |
| url | http://psasir.upm.edu.my/id/eprint/60884/1/Anti-elastase%2C%20anti-collagenase%20and%20antimicrobial%20activities%20of%20the%20underutilized%20red%20pitaya%20peel%20an%20in-vitro%20study%20for%20anti-aging%20applications.pdf |
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