Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review
The inflammation process in the human body plays a central role in the pathogenesis of many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a decisive role in human body, particularly in physiological and pathological process. The chronic inflammation state could gener...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Springer
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61258/1/ROS.pdf |
| _version_ | 1796977438329143296 |
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| author | Ranneh, Yazan Ali, Faisal Md Akim, Abdah Ab. Hamid, Hasiah Khazaai, Huzwah Fadel, Abdulmannan |
| author_facet | Ranneh, Yazan Ali, Faisal Md Akim, Abdah Ab. Hamid, Hasiah Khazaai, Huzwah Fadel, Abdulmannan |
| author_sort | Ranneh, Yazan |
| collection | UPM |
| description | The inflammation process in the human body plays a central role in the pathogenesis of many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a decisive role in human body, particularly in physiological and pathological process. The chronic inflammation state could generate several types of diseases such as cancer, atherosclerosis, diabetes mellitus and arthritis, especially if it is concomitant with high levels of pro-inflammatory markers and ROS. The respiratory burst of inflammatory cells during inflammation increases the production and accumulation of ROS. However, ROS regulate various types of kinases and transcription factors such nuclear factor-kappa B which is related to the activation of pro-inflammatory genes. The exact crosstalk between pro-inflammatory markers and ROS in terms of pathogenesis and development of serious diseases is still ambitious. Many studies have been attempting to determine the mechanistic mutual relationship between ROS and pro-inflammatory markers. Therefore hereby, we review the hypothetical relationship between ROS and pro-inflammatory markers in which they have been proposed to initiate cancer, atherosclerosis, diabetes mellitus and arthritis. |
| first_indexed | 2024-03-06T09:40:07Z |
| format | Article |
| id | upm.eprints-61258 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:40:07Z |
| publishDate | 2017 |
| publisher | Springer |
| record_format | dspace |
| spelling | upm.eprints-612582021-07-17T22:30:28Z http://psasir.upm.edu.my/id/eprint/61258/ Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review Ranneh, Yazan Ali, Faisal Md Akim, Abdah Ab. Hamid, Hasiah Khazaai, Huzwah Fadel, Abdulmannan The inflammation process in the human body plays a central role in the pathogenesis of many chronic diseases. In addition, reactive oxygen species (ROS) exert potentially a decisive role in human body, particularly in physiological and pathological process. The chronic inflammation state could generate several types of diseases such as cancer, atherosclerosis, diabetes mellitus and arthritis, especially if it is concomitant with high levels of pro-inflammatory markers and ROS. The respiratory burst of inflammatory cells during inflammation increases the production and accumulation of ROS. However, ROS regulate various types of kinases and transcription factors such nuclear factor-kappa B which is related to the activation of pro-inflammatory genes. The exact crosstalk between pro-inflammatory markers and ROS in terms of pathogenesis and development of serious diseases is still ambitious. Many studies have been attempting to determine the mechanistic mutual relationship between ROS and pro-inflammatory markers. Therefore hereby, we review the hypothetical relationship between ROS and pro-inflammatory markers in which they have been proposed to initiate cancer, atherosclerosis, diabetes mellitus and arthritis. Springer 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/61258/1/ROS.pdf Ranneh, Yazan and Ali, Faisal and Md Akim, Abdah and Ab. Hamid, Hasiah and Khazaai, Huzwah and Fadel, Abdulmannan (2017) Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review. Applied Biological Chemistry, 60 (3). pp. 327-338. ISSN 2468-0834; ESSN: 2468-0842 https://applbiolchem.springeropen.com/articles/10.1007/s13765-017-0285-9 10.1007/s13765-017-0285-9 |
| spellingShingle | Ranneh, Yazan Ali, Faisal Md Akim, Abdah Ab. Hamid, Hasiah Khazaai, Huzwah Fadel, Abdulmannan Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title | Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title_full | Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title_fullStr | Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title_full_unstemmed | Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title_short | Crosstalk between reactive oxygen species and pro-inflammatory markers in developing various chronic diseases: a review |
| title_sort | crosstalk between reactive oxygen species and pro inflammatory markers in developing various chronic diseases a review |
| url | http://psasir.upm.edu.my/id/eprint/61258/1/ROS.pdf |
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