Curcumin, piperine, and capsaicin: a comparative study of spice-mediated inhibition of human cytochrome P450 isozyme activities
Inhibition of cytochrome P450 (P450) enzymes (CYP) has been shown to lower the metabolism of drugs that are P450 substrates and to consequently alter their pharmacokinetic profiles. Curcumin (CUR), piperine (PIP), and capsaicin (CAP) are spice components (SC) that inhibit the activities of a range o...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Pharmacology and Experimental Therapeutics (ASPET)
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/61267/1/Curcumin%2C%20piperine%2C%20and%20capsaicin%20a%20comparative%20study%20of%20spice-mediated%20inhibition%20of%20human%20cytochrome%20P450%20isozyme%20activities.pdf |