Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy
Introduction: Malnutrition is associated with poorer outcomes following treatment for colorectal cancer (CRC). This study evaluates the relationship between nutritional status using scored Patient Generated-Subjective Global Assessment (PG-SGA) with the validated European Organisation for Researc...
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| Format: | Article |
| Language: | English |
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Nutrition Society of Malaysia
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/62943/1/Relationship%20between%20quality%20of%20life%20and%20nutritional%20status%20in%20colorectal%20cancer%20patients%20undergoing%20chemotherapy.pdf |
| _version_ | 1796977673387376640 |
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| author | Abu Zaid, Zalina Jackson, Kathryn Cobiac, Lynne Kandiah, Mirnalini |
| author_facet | Abu Zaid, Zalina Jackson, Kathryn Cobiac, Lynne Kandiah, Mirnalini |
| author_sort | Abu Zaid, Zalina |
| collection | UPM |
| description | Introduction: Malnutrition is associated with poorer outcomes following treatment for colorectal cancer (CRC). This study evaluates the relationship between nutritional status using scored Patient Generated-Subjective Global Assessment (PG-SGA) with the validated European Organisation for Research and Treatment of Cancer questionnaire (EORTC-QLQ C30) which consists of five functional scales, three symptoms scales and one item of global health/quality of life (QOL). Methods: A total of 42 CRC patients at oncology outpatient clinics from two hospitals in Malaysia participated in the study from March 2011 to March 2012. The participants were classified as either well-nourished (PG-SGA A) or malnourished (PG-SGA B and C). Results: The majority of patients were Chinese, male, with a mean age of 57.1 ± 9.8 years and had been diagnosed with stage 2 CRC. Well-nourished patients had statistically significantly better QOL scores on symptom scales: fatigue (p<0.001), nausea and vomiting (p<0.05), and pain (p<0.001) compared to malnourished patients. PG-SGA was strongly correlated with the main domains of the QOL: global health status (r = -0.395, p<0.05), fatigue (r = 0.816, p<0.001), nausea and vomiting (r = 0.730, p<0.001) and pain (r = 0.629,p<0.001). The better the nutritional status (lower total mean score of PG-SGA), the higher the QOL (high mean score of global health status). Conclusion: The scored PG-SGA is suitable for use as a nutrition assessment tool to identify malnutrition and it is associated with QOL among this population. |
| first_indexed | 2024-03-06T09:43:32Z |
| format | Article |
| id | upm.eprints-62943 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:43:32Z |
| publishDate | 2017 |
| publisher | Nutrition Society of Malaysia |
| record_format | dspace |
| spelling | upm.eprints-629432018-09-28T10:44:34Z http://psasir.upm.edu.my/id/eprint/62943/ Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy Abu Zaid, Zalina Jackson, Kathryn Cobiac, Lynne Kandiah, Mirnalini Introduction: Malnutrition is associated with poorer outcomes following treatment for colorectal cancer (CRC). This study evaluates the relationship between nutritional status using scored Patient Generated-Subjective Global Assessment (PG-SGA) with the validated European Organisation for Research and Treatment of Cancer questionnaire (EORTC-QLQ C30) which consists of five functional scales, three symptoms scales and one item of global health/quality of life (QOL). Methods: A total of 42 CRC patients at oncology outpatient clinics from two hospitals in Malaysia participated in the study from March 2011 to March 2012. The participants were classified as either well-nourished (PG-SGA A) or malnourished (PG-SGA B and C). Results: The majority of patients were Chinese, male, with a mean age of 57.1 ± 9.8 years and had been diagnosed with stage 2 CRC. Well-nourished patients had statistically significantly better QOL scores on symptom scales: fatigue (p<0.001), nausea and vomiting (p<0.05), and pain (p<0.001) compared to malnourished patients. PG-SGA was strongly correlated with the main domains of the QOL: global health status (r = -0.395, p<0.05), fatigue (r = 0.816, p<0.001), nausea and vomiting (r = 0.730, p<0.001) and pain (r = 0.629,p<0.001). The better the nutritional status (lower total mean score of PG-SGA), the higher the QOL (high mean score of global health status). Conclusion: The scored PG-SGA is suitable for use as a nutrition assessment tool to identify malnutrition and it is associated with QOL among this population. Nutrition Society of Malaysia 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/62943/1/Relationship%20between%20quality%20of%20life%20and%20nutritional%20status%20in%20colorectal%20cancer%20patients%20undergoing%20chemotherapy.pdf Abu Zaid, Zalina and Jackson, Kathryn and Cobiac, Lynne and Kandiah, Mirnalini (2017) Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy. Malaysian Journal of Nutrition, 23 (3). 375 - 384. ISSN 1394-035X http://www.nutriweb.org.my/publications/mjn0023_3/7Zalina673(edSP)K2%20(1).pdf |
| spellingShingle | Abu Zaid, Zalina Jackson, Kathryn Cobiac, Lynne Kandiah, Mirnalini Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title | Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title_full | Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title_fullStr | Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title_full_unstemmed | Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title_short | Relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| title_sort | relationship between quality of life and nutritional status in colorectal cancer patients undergoing chemotherapy |
| url | http://psasir.upm.edu.my/id/eprint/62943/1/Relationship%20between%20quality%20of%20life%20and%20nutritional%20status%20in%20colorectal%20cancer%20patients%20undergoing%20chemotherapy.pdf |
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