Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency

In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasi...

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Main Authors: Mat Rusni, Izyani, Ismail, Alyani
Format: Conference or Workshop Item
Language:English
Published: IEEE 2017
Online Access:http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf
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author Mat Rusni, Izyani
Ismail, Alyani
author_facet Mat Rusni, Izyani
Ismail, Alyani
author_sort Mat Rusni, Izyani
collection UPM
description In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasive at low power level and yet its label free. The resonant frequency of the sensor is measured as 4.96 GHz. The shift in resonant frequency is employed as the sensor output for deoxyribonucleic acid (DNA) detection. The resonance frequency is shifted to the left when single stranded deoxyribonucleic acid (ssDNA) is immobilized onto gold surface and further shifted when hybridization or the binding event between the molecule of ssDNA and cDNA occurred. The sensitivity of this biosensor is up to 10 MHz/Molar with the detection limit of Molar is conducted during this experiment.
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spelling upm.eprints-646392018-08-13T03:16:31Z http://psasir.upm.edu.my/id/eprint/64639/ Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency Mat Rusni, Izyani Ismail, Alyani In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasive at low power level and yet its label free. The resonant frequency of the sensor is measured as 4.96 GHz. The shift in resonant frequency is employed as the sensor output for deoxyribonucleic acid (DNA) detection. The resonance frequency is shifted to the left when single stranded deoxyribonucleic acid (ssDNA) is immobilized onto gold surface and further shifted when hybridization or the binding event between the molecule of ssDNA and cDNA occurred. The sensitivity of this biosensor is up to 10 MHz/Molar with the detection limit of Molar is conducted during this experiment. IEEE 2017 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf Mat Rusni, Izyani and Ismail, Alyani (2017) Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency. In: 2017 6th International Conference on Electrical Engineering and Informatics (ICEEI), 25-27 Nov. 2017, Langkawi, Kedah. . 10.1109/ICEEI.2017.8312402
spellingShingle Mat Rusni, Izyani
Ismail, Alyani
Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title_full Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title_fullStr Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title_full_unstemmed Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title_short Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
title_sort aligned gap multiple split ring resonator biosensor for dna hybridization detection at microwave frequency
url http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf
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