Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency
In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasi...
Main Authors: | , |
---|---|
Format: | Conference or Workshop Item |
Language: | English |
Published: |
IEEE
2017
|
Online Access: | http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf |
_version_ | 1796977937667325952 |
---|---|
author | Mat Rusni, Izyani Ismail, Alyani |
author_facet | Mat Rusni, Izyani Ismail, Alyani |
author_sort | Mat Rusni, Izyani |
collection | UPM |
description | In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasive at low power level and yet its label free. The resonant frequency of the sensor is measured as 4.96 GHz. The shift in resonant frequency is employed as the sensor output for deoxyribonucleic acid (DNA) detection. The resonance frequency is shifted to the left when single stranded deoxyribonucleic acid (ssDNA) is immobilized onto gold surface and further shifted when hybridization or the binding event between the molecule of ssDNA and cDNA occurred. The sensitivity of this biosensor is up to 10 MHz/Molar with the detection limit of Molar is conducted during this experiment. |
first_indexed | 2024-03-06T09:47:22Z |
format | Conference or Workshop Item |
id | upm.eprints-64639 |
institution | Universiti Putra Malaysia |
language | English |
last_indexed | 2024-03-06T09:47:22Z |
publishDate | 2017 |
publisher | IEEE |
record_format | dspace |
spelling | upm.eprints-646392018-08-13T03:16:31Z http://psasir.upm.edu.my/id/eprint/64639/ Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency Mat Rusni, Izyani Ismail, Alyani In this paper, the interest of microwave signals for biological detection applications using metamaterial structure as a biosensor element has been demonstrated. Microwave sensing is highly challenging for biological detection as it presents the attractive advantages of being contactless, non-invasive at low power level and yet its label free. The resonant frequency of the sensor is measured as 4.96 GHz. The shift in resonant frequency is employed as the sensor output for deoxyribonucleic acid (DNA) detection. The resonance frequency is shifted to the left when single stranded deoxyribonucleic acid (ssDNA) is immobilized onto gold surface and further shifted when hybridization or the binding event between the molecule of ssDNA and cDNA occurred. The sensitivity of this biosensor is up to 10 MHz/Molar with the detection limit of Molar is conducted during this experiment. IEEE 2017 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf Mat Rusni, Izyani and Ismail, Alyani (2017) Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency. In: 2017 6th International Conference on Electrical Engineering and Informatics (ICEEI), 25-27 Nov. 2017, Langkawi, Kedah. . 10.1109/ICEEI.2017.8312402 |
spellingShingle | Mat Rusni, Izyani Ismail, Alyani Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title | Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title_full | Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title_fullStr | Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title_full_unstemmed | Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title_short | Aligned gap multiple split ring resonator biosensor for DNA hybridization detection at microwave frequency |
title_sort | aligned gap multiple split ring resonator biosensor for dna hybridization detection at microwave frequency |
url | http://psasir.upm.edu.my/id/eprint/64639/1/Aligned%20gap%20multiple%20split%20ring%20resonator%20biosensor%20for%20DNA%20hybridization%20detection%20at%20microwave%20frequency.pdf |
work_keys_str_mv | AT matrusniizyani alignedgapmultiplesplitringresonatorbiosensorfordnahybridizationdetectionatmicrowavefrequency AT ismailalyani alignedgapmultiplesplitringresonatorbiosensorfordnahybridizationdetectionatmicrowavefrequency |