Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus
Newcastle disease (ND) is highly contagious disease that can caused high mortality up to 100% in susceptible chickens. Although antibody response is the main immune response that confers protection, the involvement of cell-mediated immunity is not clear. Similar to mammals, chickens also have Natura...
| Main Authors: | , , , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
Faculty of Veterinary Medicine, Universiti Putra Malaysia
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/65040/1/PA-39.pdf |
| _version_ | 1825932869110857728 |
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| author | Abdolmaleki, Mostafa Tan, Sheau Wei Yeap, Swee Keong Satharasinghe, Dilan Amila Jahromi, Mohammad Zareian Omar, Abdul Rahman Ideris, Aini |
| author_facet | Abdolmaleki, Mostafa Tan, Sheau Wei Yeap, Swee Keong Satharasinghe, Dilan Amila Jahromi, Mohammad Zareian Omar, Abdul Rahman Ideris, Aini |
| author_sort | Abdolmaleki, Mostafa |
| collection | UPM |
| description | Newcastle disease (ND) is highly contagious disease that can caused high mortality up to 100% in susceptible chickens. Although antibody response is the main immune response that confers protection, the involvement of cell-mediated immunity is not clear. Similar to mammals, chickens also have Natural Killer (NK) cells which were first described in 1975 as cytotoxic lymphocytes and they play an important role in the early defense against viruses. They have been widely investigated in various mammalian species, but their role in chicken is poorly understood. Here, we isolated and examined intestinal intra-epithelial lymphocytes (IEL) NK cells population changes following infection with velogenic genotype VIII and LaSota vaccine strain. Flow cytometry analysis indicated that the IEL-NK cells population of chickens infected with velogenic genotype VIII NDV was significant decreased compared to LaSota and control groups. |
| first_indexed | 2024-03-06T09:48:34Z |
| format | Conference or Workshop Item |
| id | upm.eprints-65040 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:48:34Z |
| publishDate | 2015 |
| publisher | Faculty of Veterinary Medicine, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-650402018-09-03T04:49:38Z http://psasir.upm.edu.my/id/eprint/65040/ Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus Abdolmaleki, Mostafa Tan, Sheau Wei Yeap, Swee Keong Satharasinghe, Dilan Amila Jahromi, Mohammad Zareian Omar, Abdul Rahman Ideris, Aini Newcastle disease (ND) is highly contagious disease that can caused high mortality up to 100% in susceptible chickens. Although antibody response is the main immune response that confers protection, the involvement of cell-mediated immunity is not clear. Similar to mammals, chickens also have Natural Killer (NK) cells which were first described in 1975 as cytotoxic lymphocytes and they play an important role in the early defense against viruses. They have been widely investigated in various mammalian species, but their role in chicken is poorly understood. Here, we isolated and examined intestinal intra-epithelial lymphocytes (IEL) NK cells population changes following infection with velogenic genotype VIII and LaSota vaccine strain. Flow cytometry analysis indicated that the IEL-NK cells population of chickens infected with velogenic genotype VIII NDV was significant decreased compared to LaSota and control groups. Faculty of Veterinary Medicine, Universiti Putra Malaysia 2015 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/65040/1/PA-39.pdf Abdolmaleki, Mostafa and Tan, Sheau Wei and Yeap, Swee Keong and Satharasinghe, Dilan Amila and Jahromi, Mohammad Zareian and Omar, Abdul Rahman and Ideris, Aini (2015) Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus. In: World Veterinary Poultry Association (Malaysia Branch) and World's Poultry Science Association (Malaysia Branch) Scientific Conference 2015, 21-22 Sept. 2015, Kuala Lumpur Convention Centre, Kuala Lumpur, Malaysia. (pp. 192-193). |
| spellingShingle | Abdolmaleki, Mostafa Tan, Sheau Wei Yeap, Swee Keong Satharasinghe, Dilan Amila Jahromi, Mohammad Zareian Omar, Abdul Rahman Ideris, Aini Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title | Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title_full | Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title_fullStr | Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title_full_unstemmed | Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title_short | Alteration in intraepitheliallymphocyte-natural killer (IEL-NK) cell populations following infection with differrnt strains of Newcastle disease virus |
| title_sort | alteration in intraepitheliallymphocyte natural killer iel nk cell populations following infection with differrnt strains of newcastle disease virus |
| url | http://psasir.upm.edu.my/id/eprint/65040/1/PA-39.pdf |
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