Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression
Chromobacterium violaceum is a pathogenic bacteria to human and produce antibiotics which include aerocyanidine, aerocavin, 3,6-dihydroxyindoxazene, Factor Y-T0678H (6-hydroxy-3-oxo-1,2-benzisoxazolin) and violacein, a purple pigment that gives Chromobacterium violaceum its colour. The production of...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/65141/1/PGM-1-23.pdf |
| _version_ | 1825932889106153472 |
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| author | Loke, Wai Keong Mohd Saud, Halimi |
| author_facet | Loke, Wai Keong Mohd Saud, Halimi |
| author_sort | Loke, Wai Keong |
| collection | UPM |
| description | Chromobacterium violaceum is a pathogenic bacteria to human and produce antibiotics which include aerocyanidine, aerocavin, 3,6-dihydroxyindoxazene, Factor Y-T0678H (6-hydroxy-3-oxo-1,2-benzisoxazolin) and violacein, a purple pigment that gives Chromobacterium violaceum its colour. The production of purple pigment and antibiotics were controlled by quorum sensing and activated by N-acyl homoserine lactones (AHL) C6-HSL signal molecules in high cell density condition and reaches the quorum level. In high concentration of glucose, the production of purple pigment and antibiotics from C. violaceum was affected and was produced only at low nondetectable volume. This phenomenon showed that catabolite repression happened in C. violaceum and the operon to control the genes of production of purple pigment and other antibiotics were catabolite-sensitive where the operon was not maximally expressed. |
| first_indexed | 2024-03-06T09:48:52Z |
| format | Conference or Workshop Item |
| id | upm.eprints-65141 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:48:52Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | upm.eprints-651412018-09-04T04:14:49Z http://psasir.upm.edu.my/id/eprint/65141/ Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression Loke, Wai Keong Mohd Saud, Halimi Chromobacterium violaceum is a pathogenic bacteria to human and produce antibiotics which include aerocyanidine, aerocavin, 3,6-dihydroxyindoxazene, Factor Y-T0678H (6-hydroxy-3-oxo-1,2-benzisoxazolin) and violacein, a purple pigment that gives Chromobacterium violaceum its colour. The production of purple pigment and antibiotics were controlled by quorum sensing and activated by N-acyl homoserine lactones (AHL) C6-HSL signal molecules in high cell density condition and reaches the quorum level. In high concentration of glucose, the production of purple pigment and antibiotics from C. violaceum was affected and was produced only at low nondetectable volume. This phenomenon showed that catabolite repression happened in C. violaceum and the operon to control the genes of production of purple pigment and other antibiotics were catabolite-sensitive where the operon was not maximally expressed. 2009 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/65141/1/PGM-1-23.pdf Loke, Wai Keong and Mohd Saud, Halimi (2009) Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression. In: 8th Malaysia Congress on Genetics, 4-6 Aug. 2009, Genting Highlands, Malaysia. (pp. 402-406). |
| spellingShingle | Loke, Wai Keong Mohd Saud, Halimi Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title | Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title_full | Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title_fullStr | Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title_full_unstemmed | Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title_short | Inhibition of Chromobacterium violaceum antibiotics production by catabolite repression |
| title_sort | inhibition of chromobacterium violaceum antibiotics production by catabolite repression |
| url | http://psasir.upm.edu.my/id/eprint/65141/1/PGM-1-23.pdf |
| work_keys_str_mv | AT lokewaikeong inhibitionofchromobacteriumviolaceumantibioticsproductionbycataboliterepression AT mohdsaudhalimi inhibitionofchromobacteriumviolaceumantibioticsproductionbycataboliterepression |