Production of lentiviral vector with polycistronic transcripts for reprogramming of mouse fibroblast cells
iPS cells were originally generated using monocistronic retroviral vectors carrying the Yamanaka factors 'OSKM'. The development of a polycistronic viral vector with OSKM linked by 2A peptides has simplified reprogramming procedure and reduced the risk of multiple proviral integrations and...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universiti Putra Malaysia Press
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/66290/1/10%20JST%20Vol%2026%20%282%29%20Apr%202018_JST-0759-2016_pg627-640.pdf |