Primary localized amyloidosis in nasopharynx: a case report
Nasopharyngeal amyloidosis is an extremely rare benign tumour. It is divided into localized or systemic amyloidosis. It is more common in men. Clinical presentation includes nasal blockage, epistaxis and reduced hearing. Classical positive Congo red stain and appearance of apple green birefringence...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/69562/1/2019060311394421_MJMHS_June_2019.pdf |
| _version_ | 1825933745596661760 |
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| author | Naserrudin, Nadia Syafeera Ainer, Indumathi Liew, Kong Yew Ishak, Azlan Iskandar Gnanasegaram, Hemlata Kumari |
| author_facet | Naserrudin, Nadia Syafeera Ainer, Indumathi Liew, Kong Yew Ishak, Azlan Iskandar Gnanasegaram, Hemlata Kumari |
| author_sort | Naserrudin, Nadia Syafeera |
| collection | UPM |
| description | Nasopharyngeal amyloidosis is an extremely rare benign tumour. It is divided into localized or systemic amyloidosis. It is more common in men. Clinical presentation includes nasal blockage, epistaxis and reduced hearing. Classical positive Congo red stain and appearance of apple green birefringence on polarized microscopy confirms the diagnosis of amyloidosis. We present a case of nasopharyngeal amyloidosis in a 44-year old lady who presented with acute hearing loss for 1 week with epistaxis mimicking nasopharyngeal carcinoma. Clinical examination showed a nasopharyngeal mass with biopsy proven AA amyloidosis. She is now cured of amyloidosis following endoscopic transnasal excision of tumour. We discuss on the similarity of presentation between nasopharyngeal carcinoma; the commonest malignant tumour in our region and the much rarer nasopharyngeal amyloidosis as well as highlighting the importance in early recognition of the latter in view of its known risk of systemic involvement. |
| first_indexed | 2024-03-06T10:02:04Z |
| format | Article |
| id | upm.eprints-69562 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:02:04Z |
| publishDate | 2019 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-695622019-07-04T04:59:48Z http://psasir.upm.edu.my/id/eprint/69562/ Primary localized amyloidosis in nasopharynx: a case report Naserrudin, Nadia Syafeera Ainer, Indumathi Liew, Kong Yew Ishak, Azlan Iskandar Gnanasegaram, Hemlata Kumari Nasopharyngeal amyloidosis is an extremely rare benign tumour. It is divided into localized or systemic amyloidosis. It is more common in men. Clinical presentation includes nasal blockage, epistaxis and reduced hearing. Classical positive Congo red stain and appearance of apple green birefringence on polarized microscopy confirms the diagnosis of amyloidosis. We present a case of nasopharyngeal amyloidosis in a 44-year old lady who presented with acute hearing loss for 1 week with epistaxis mimicking nasopharyngeal carcinoma. Clinical examination showed a nasopharyngeal mass with biopsy proven AA amyloidosis. She is now cured of amyloidosis following endoscopic transnasal excision of tumour. We discuss on the similarity of presentation between nasopharyngeal carcinoma; the commonest malignant tumour in our region and the much rarer nasopharyngeal amyloidosis as well as highlighting the importance in early recognition of the latter in view of its known risk of systemic involvement. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/69562/1/2019060311394421_MJMHS_June_2019.pdf Naserrudin, Nadia Syafeera and Ainer, Indumathi and Liew, Kong Yew and Ishak, Azlan Iskandar and Gnanasegaram, Hemlata Kumari (2019) Primary localized amyloidosis in nasopharynx: a case report. Malaysian Journal of Medicine and Health Sciences, 15 (2). pp. 151-153. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019060311394421_MJMHS_June_2019.pdf |
| spellingShingle | Naserrudin, Nadia Syafeera Ainer, Indumathi Liew, Kong Yew Ishak, Azlan Iskandar Gnanasegaram, Hemlata Kumari Primary localized amyloidosis in nasopharynx: a case report |
| title | Primary localized amyloidosis in nasopharynx: a case report |
| title_full | Primary localized amyloidosis in nasopharynx: a case report |
| title_fullStr | Primary localized amyloidosis in nasopharynx: a case report |
| title_full_unstemmed | Primary localized amyloidosis in nasopharynx: a case report |
| title_short | Primary localized amyloidosis in nasopharynx: a case report |
| title_sort | primary localized amyloidosis in nasopharynx a case report |
| url | http://psasir.upm.edu.my/id/eprint/69562/1/2019060311394421_MJMHS_June_2019.pdf |
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