Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4
Bacteria and their metabolites are shown to be a potential therapeutic agent for cancer treatment. Much attention has been directed to Lactic acid bacteria (LAB) which exhibits several killing mechanisms via invasion and colonization of solid tumors. Discovery of the characteristics of postbiotic me...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/70056/1/2019070210033012_MJMHS_SP2_2019.pdf |
| _version_ | 1796979062267183104 |
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| author | Muhamad Zakuan, Noraina Foo, Hooi Ling Saiful Yazan, Latifah |
| author_facet | Muhamad Zakuan, Noraina Foo, Hooi Ling Saiful Yazan, Latifah |
| author_sort | Muhamad Zakuan, Noraina |
| collection | UPM |
| description | Bacteria and their metabolites are shown to be a potential therapeutic agent for cancer treatment. Much attention has been directed to Lactic acid bacteria (LAB) which exhibits several killing mechanisms via invasion and colonization of solid tumors. Discovery of the characteristics of postbiotic metabolites that exert the same probiotic effects has attracted immense attention towards anti-cancer effect. It is known that LAB improves health and composition of microbiota in the gut. Supplementation of LAB is proven to enhance the host immunity and modulation of the immune system to fight diseases including cancers. Lactobacillus plantarum I-UL4 is the LAB species isolated from Malaysian fermented food, Tapai Ubi which capable of producing bioactive metabolic products. In this review, the properties of UL4-PPM will be discussed including anti-microbial, anti-cancer and immunomodulatory effects. Overall, it would be beneficial to discover the potential effects of UL4-PPM to possibly serve as an alternative treatment for cancer. |
| first_indexed | 2024-03-06T10:03:33Z |
| format | Article |
| id | upm.eprints-70056 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:03:33Z |
| publishDate | 2019 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-700562019-08-16T00:39:08Z http://psasir.upm.edu.my/id/eprint/70056/ Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 Muhamad Zakuan, Noraina Foo, Hooi Ling Saiful Yazan, Latifah Bacteria and their metabolites are shown to be a potential therapeutic agent for cancer treatment. Much attention has been directed to Lactic acid bacteria (LAB) which exhibits several killing mechanisms via invasion and colonization of solid tumors. Discovery of the characteristics of postbiotic metabolites that exert the same probiotic effects has attracted immense attention towards anti-cancer effect. It is known that LAB improves health and composition of microbiota in the gut. Supplementation of LAB is proven to enhance the host immunity and modulation of the immune system to fight diseases including cancers. Lactobacillus plantarum I-UL4 is the LAB species isolated from Malaysian fermented food, Tapai Ubi which capable of producing bioactive metabolic products. In this review, the properties of UL4-PPM will be discussed including anti-microbial, anti-cancer and immunomodulatory effects. Overall, it would be beneficial to discover the potential effects of UL4-PPM to possibly serve as an alternative treatment for cancer. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/70056/1/2019070210033012_MJMHS_SP2_2019.pdf Muhamad Zakuan, Noraina and Foo, Hooi Ling and Saiful Yazan, Latifah (2019) Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 81-84. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019070210033012_MJMHS_SP2_2019.pdf |
| spellingShingle | Muhamad Zakuan, Noraina Foo, Hooi Ling Saiful Yazan, Latifah Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title | Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title_full | Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title_fullStr | Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title_full_unstemmed | Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title_short | Anti-microbial, anti-cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by Lactobacillus plantarum I-UL4 |
| title_sort | anti microbial anti cancer and immunomodulatory properties of proteinaceous postbiotic metabolite produced by lactobacillus plantarum i ul4 |
| url | http://psasir.upm.edu.my/id/eprint/70056/1/2019070210033012_MJMHS_SP2_2019.pdf |
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