Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report
We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urin...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf |
| _version_ | 1825933844409221120 |
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| author | Othman, Shuhaidah Philip, Noraini Mohd Taib, Niazlin Neela, Vasantha Kumari Chee, Hui Yee |
| author_facet | Othman, Shuhaidah Philip, Noraini Mohd Taib, Niazlin Neela, Vasantha Kumari Chee, Hui Yee |
| author_sort | Othman, Shuhaidah |
| collection | UPM |
| description | We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urine samples collected on 4th day of admission were negative for leptospires culture and serological method showed no significant evidences of positive infection. Molecular detection of Leptospira spp. in blood sample was positive but not in urine sample. After seven weeks of infection, leptospiral DNA was detected in urine sample using molecular method. |
| first_indexed | 2024-03-06T10:03:34Z |
| format | Article |
| id | upm.eprints-70062 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:03:34Z |
| publishDate | 2019 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-700622019-08-16T00:39:29Z http://psasir.upm.edu.my/id/eprint/70062/ Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report Othman, Shuhaidah Philip, Noraini Mohd Taib, Niazlin Neela, Vasantha Kumari Chee, Hui Yee We described a case of positive molecular detection of leptospirosis in urine sample following prolonged hospitalization. Relevant clinical history had raised suspicion to leptospirosis infection. A significantly high level of creatinine kinase suggested possibility of rhabdomyolysis. Blood and urine samples collected on 4th day of admission were negative for leptospires culture and serological method showed no significant evidences of positive infection. Molecular detection of Leptospira spp. in blood sample was positive but not in urine sample. After seven weeks of infection, leptospiral DNA was detected in urine sample using molecular method. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf Othman, Shuhaidah and Philip, Noraini and Mohd Taib, Niazlin and Neela, Vasantha Kumari and Chee, Hui Yee (2019) Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 105-107. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2019070210045015_MJMHS_SP2_2019.pdf |
| spellingShingle | Othman, Shuhaidah Philip, Noraini Mohd Taib, Niazlin Neela, Vasantha Kumari Chee, Hui Yee Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title | Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title_full | Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title_fullStr | Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title_full_unstemmed | Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title_short | Detection of leptospiral DNA in urine sample following prolonged hospitalization: a case report |
| title_sort | detection of leptospiral dna in urine sample following prolonged hospitalization a case report |
| url | http://psasir.upm.edu.my/id/eprint/70062/1/2019070210045015_MJMHS_SP2_2019.pdf |
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