Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2
Forty clinically healthy goats at the age of approximately 7 months were equally divided into four groups. Those in Group 1, 2 and 3 were intranasally exposed to 1 mg, 1.5 mg and 2 mg of lyophilize crude containing 1.0x106 cfu/mL of P. multocida B2, respectively. The procedure was then repeated two...
| Main Authors: | , , |
|---|---|
| Format: | Conference or Workshop Item |
| Published: |
2007
|
| _version_ | 1825944131254353920 |
|---|---|
| author | Abd Wahid, Mohd Effendy Ooi, Keng Wooi Saad, Mohd Zamri |
| author_facet | Abd Wahid, Mohd Effendy Ooi, Keng Wooi Saad, Mohd Zamri |
| author_sort | Abd Wahid, Mohd Effendy |
| collection | UPM |
| description | Forty clinically healthy goats at the age of approximately 7 months were equally divided into four groups. Those in Group 1, 2 and 3 were intranasally exposed to 1 mg, 1.5 mg and 2 mg of lyophilize crude containing 1.0x106 cfu/mL of P. multocida B2, respectively. The procedure was then repeated two weeks after the first inoculation. Group 4 remained as the untreated control group. ELISA was used to determine the levels of IgA and IgG in the serum and lung lavage fluids, while the right apical lobes lungs were cut into seven sections and examined for the sizes of bronchus-associated lymphoid tissues (BALT) and numbers of lymphocytes. Results showed that the levels of serum IgA and IgG were significantly higher (p<0.01) at 1.5 mg and 2 mg doses. Concurrently, the levels of IgA and IgG of the lung lavages were significantly higher (p<0.05) in all treated groups. The sizes of BALT and numbers of lymphocytes were significantly higher (p<0.05) after the first and second inoculation of 2 mg of the crude. |
| first_indexed | 2024-03-06T07:11:04Z |
| format | Conference or Workshop Item |
| id | upm.eprints-7043 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T07:11:04Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | upm.eprints-70432014-11-18T06:30:09Z http://psasir.upm.edu.my/id/eprint/7043/ Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 Abd Wahid, Mohd Effendy Ooi, Keng Wooi Saad, Mohd Zamri Forty clinically healthy goats at the age of approximately 7 months were equally divided into four groups. Those in Group 1, 2 and 3 were intranasally exposed to 1 mg, 1.5 mg and 2 mg of lyophilize crude containing 1.0x106 cfu/mL of P. multocida B2, respectively. The procedure was then repeated two weeks after the first inoculation. Group 4 remained as the untreated control group. ELISA was used to determine the levels of IgA and IgG in the serum and lung lavage fluids, while the right apical lobes lungs were cut into seven sections and examined for the sizes of bronchus-associated lymphoid tissues (BALT) and numbers of lymphocytes. Results showed that the levels of serum IgA and IgG were significantly higher (p<0.01) at 1.5 mg and 2 mg doses. Concurrently, the levels of IgA and IgG of the lung lavages were significantly higher (p<0.05) in all treated groups. The sizes of BALT and numbers of lymphocytes were significantly higher (p<0.05) after the first and second inoculation of 2 mg of the crude. 2007 Conference or Workshop Item PeerReviewed Abd Wahid, Mohd Effendy and Ooi, Keng Wooi and Saad, Mohd Zamri (2007) Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2. In: 12th International Conference of the Association of Institutions for Tropical Veterinary Medicine (AITVM), 20-22 Aug. 2007, Montpellier, France. (pp. 195-200). |
| spellingShingle | Abd Wahid, Mohd Effendy Ooi, Keng Wooi Saad, Mohd Zamri Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title | Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title_full | Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title_fullStr | Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title_full_unstemmed | Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title_short | Stimulation of bronchus-associated lymphoid tissue against Pasteurella multocida B:2 |
| title_sort | stimulation of bronchus associated lymphoid tissue against pasteurella multocida b 2 |
| work_keys_str_mv | AT abdwahidmohdeffendy stimulationofbronchusassociatedlymphoidtissueagainstpasteurellamultocidab2 AT ooikengwooi stimulationofbronchusassociatedlymphoidtissueagainstpasteurellamultocidab2 AT saadmohdzamri stimulationofbronchusassociatedlymphoidtissueagainstpasteurellamultocidab2 |