Pharmacogenetics of CYP450A, ABCB1, ABCC2, SLCO1B3 gene polymorphisms and plasma alpha-1-acid glycoprotein level on nonhaematological adverse events of docetaxel in Malaysian breast cancer patients
Docetaxel is an antitubulin chemotherapeutic agent approved for the treatment of breast, lung, ovarian and non-hormonal dependent prostate cancers. However, the success of this drug is limited by adverse events (AEs), the severity of which ranges from tolerable to life threatening. Tapering the dose...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/70717/1/FPSK%28P%29%202017%2034%20IR.pdf |