Modelling the influence of ligand binding towards the structure and dynamics of protein arginine deiminase IV
An enzyme called Protein Arginine Deiminase IV (PAD4) has gained tremendous attention due to its role in rheumatoid arthritis (RA). It catalyses the citrullination reaction, whose products was reported to be dysregulated in the RA patients. Therefore, modulation of PAD4 activities is considered as a...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/71030/1/FS%202017%2082%20-%20IR.pdf |