Regulation of p53-, Bcl-2- and Caspase-dependent Signaling Pathway in Xanthorrhizol-induced Apoptosis of HepG2 Hepatoma Cells

Xanthorrhizol is a sesquiterpenoid compound extracted from the rhizome of Curcuma xanthorrhiza. This study investigated the antiproliferative effect and the mechanism of action of xanthorrhizol on human hepatoma cells, HepG2, and the mode of cell death. An antiproliferative assay using methylene blu...

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Bibliographic Details
Main Authors: Tri Handayani, Syed Alwi, Sharifah Sakinah, Nallappan, Meenakshii, Lope Pihie, Azimahtol Hawariah
Format: Article
Language:English
English
Published: International Institute of Anticancer Research (IIAR) 2007
Online Access:http://psasir.upm.edu.my/id/eprint/7266/1/Regulation%20of%20p53.pdf

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