Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia
Background: Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease in the world, particularly in Western and developed countries. It is rapidly growing in the Asia- Pacific region. Objectives: This study was designed to determine the association between risk factors and non-alcohol...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Faculty of Medicine University of Baghdad
2018
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| Online Access: | http://psasir.upm.edu.my/id/eprint/72720/1/Factors%20associated%20with%20nonalcoholic%20fatty%20liver%20disease%20grades%20.pdf |
| _version_ | 1796979508059832320 |
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| author | Khammas, Abdul Sattar Arif Mohammed, Sayed Safwan Abu Hassan, Hasyma Kadir @ Shahar, Hayati Mohamad Ibrahim, Ramlah Mohd Nasir, Nurul Nadiah M. Salih, Sarah Qahtan Mahmud, Rozi |
| author_facet | Khammas, Abdul Sattar Arif Mohammed, Sayed Safwan Abu Hassan, Hasyma Kadir @ Shahar, Hayati Mohamad Ibrahim, Ramlah Mohd Nasir, Nurul Nadiah M. Salih, Sarah Qahtan Mahmud, Rozi |
| author_sort | Khammas, Abdul Sattar Arif |
| collection | UPM |
| description | Background: Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease in the world, particularly in Western and developed countries. It is rapidly growing in the Asia- Pacific region. Objectives: This study was designed to determine the association between risk factors and non-alcoholic fatty liver disease grades among Malaysian adults. Patients and Methods: A cross-sectional observational study design was prospectively carried out in this study. Consecutive 628 respondents who attended for a medical checkup at urban health center had been recruited for the study. All respondents had the physical examination, blood tests, clinical assessments, and abdominal ultrasound. A structured self-administered questionnaire has been also used in this study in this survey. Results: From a total of 628 “health screened” subjects, 235 subjects (37.4%) were diagnosed to have non-alcoholic fatty liver disease. Female gender and Chinese race were predominant in our study population. Of those with NAFLD, more than half subjects (63.4) had a moderate grade of non-alcoholic fatty liver disease. The mean age of the study population was 54.54 ±6.69 years. Differences of the mean body mass index (BMI) and waist to hip ratio (WHR) were found to be significant among non-alcoholic fatty liver disease grades (P< 0.001). Similarly, mean triglycerides (TG) and high-densiy lipoprotein-cholesterol (HDL-C) levels had significant differences among non-alcoholic fatty liver disease grades (P< 0.001 and P= 0.016, respectively). Conclusion: the non-alcoholic fatty liver disease is common among urban Malaysian adult population. Anthropometric measurements were closely correlated with non-alcoholic fatty liver disease grades. |
| first_indexed | 2024-03-06T10:09:56Z |
| format | Article |
| id | upm.eprints-72720 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:09:56Z |
| publishDate | 2018 |
| publisher | Faculty of Medicine University of Baghdad |
| record_format | dspace |
| spelling | upm.eprints-727202021-01-29T04:47:31Z http://psasir.upm.edu.my/id/eprint/72720/ Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia Khammas, Abdul Sattar Arif Mohammed, Sayed Safwan Abu Hassan, Hasyma Kadir @ Shahar, Hayati Mohamad Ibrahim, Ramlah Mohd Nasir, Nurul Nadiah M. Salih, Sarah Qahtan Mahmud, Rozi Background: Non-alcoholic fatty liver disease (NAFLD) is a very common liver disease in the world, particularly in Western and developed countries. It is rapidly growing in the Asia- Pacific region. Objectives: This study was designed to determine the association between risk factors and non-alcoholic fatty liver disease grades among Malaysian adults. Patients and Methods: A cross-sectional observational study design was prospectively carried out in this study. Consecutive 628 respondents who attended for a medical checkup at urban health center had been recruited for the study. All respondents had the physical examination, blood tests, clinical assessments, and abdominal ultrasound. A structured self-administered questionnaire has been also used in this study in this survey. Results: From a total of 628 “health screened” subjects, 235 subjects (37.4%) were diagnosed to have non-alcoholic fatty liver disease. Female gender and Chinese race were predominant in our study population. Of those with NAFLD, more than half subjects (63.4) had a moderate grade of non-alcoholic fatty liver disease. The mean age of the study population was 54.54 ±6.69 years. Differences of the mean body mass index (BMI) and waist to hip ratio (WHR) were found to be significant among non-alcoholic fatty liver disease grades (P< 0.001). Similarly, mean triglycerides (TG) and high-densiy lipoprotein-cholesterol (HDL-C) levels had significant differences among non-alcoholic fatty liver disease grades (P< 0.001 and P= 0.016, respectively). Conclusion: the non-alcoholic fatty liver disease is common among urban Malaysian adult population. Anthropometric measurements were closely correlated with non-alcoholic fatty liver disease grades. Faculty of Medicine University of Baghdad 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/72720/1/Factors%20associated%20with%20nonalcoholic%20fatty%20liver%20disease%20grades%20.pdf Khammas, Abdul Sattar Arif and Mohammed, Sayed Safwan and Abu Hassan, Hasyma and Kadir @ Shahar, Hayati and Mohamad Ibrahim, Ramlah and Mohd Nasir, Nurul Nadiah and M. Salih, Sarah Qahtan and Mahmud, Rozi (2018) Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia. Journal of the Faculty of Medicine Baghdad, 60 (1). 32 - 37. ISSN 0041-9419; ESSN: 2410-8057 https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/37 10.32007/jfacmedbagdad.60137 |
| spellingShingle | Khammas, Abdul Sattar Arif Mohammed, Sayed Safwan Abu Hassan, Hasyma Kadir @ Shahar, Hayati Mohamad Ibrahim, Ramlah Mohd Nasir, Nurul Nadiah M. Salih, Sarah Qahtan Mahmud, Rozi Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title | Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title_full | Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title_fullStr | Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title_full_unstemmed | Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title_short | Factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in Klang Valley, Malaysia |
| title_sort | factors associated with nonalcoholic fatty liver disease grades detected by ultrasound at a screening center in klang valley malaysia |
| url | http://psasir.upm.edu.my/id/eprint/72720/1/Factors%20associated%20with%20nonalcoholic%20fatty%20liver%20disease%20grades%20.pdf |
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