The crucial roles of inflammatory mediators in inflammation: a review

The inflammatory response is a crucial aspect of the tissues’ responses to deleterious inflammogens. This complex response involves leukocytes cells such as macrophages, neutrophils, and lymphocytes, also known as inflammatory cells. In response to the inflammatory process, these cells release speci...

Full description

Bibliographic Details
Main Authors: Abdulkhaleq, Layth Abdulmajeed, Assi, Mohammed Abdulrazzaq, Abdullah, Rasedee, Saad, M. Zamri, Mohd Noor, Mohd Hezmee, Yap, Taufiq Yun Hin
Format: Article
Language:English
Published: Veterinary World 2018
Online Access:http://psasir.upm.edu.my/id/eprint/74127/1/The%20crucial%20roles%20of%20inflammatory%20mediators%20in%20inflammation%20a%20review.pdf
_version_ 1796979684559290368
author Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Abdullah, Rasedee
Saad, M. Zamri
Mohd Noor, Mohd Hezmee
Yap, Taufiq Yun Hin
author_facet Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Abdullah, Rasedee
Saad, M. Zamri
Mohd Noor, Mohd Hezmee
Yap, Taufiq Yun Hin
author_sort Abdulkhaleq, Layth Abdulmajeed
collection UPM
description The inflammatory response is a crucial aspect of the tissues’ responses to deleterious inflammogens. This complex response involves leukocytes cells such as macrophages, neutrophils, and lymphocytes, also known as inflammatory cells. In response to the inflammatory process, these cells release specialized substances which include vasoactive amines and peptides, eicosanoids, proinflammatory cytokines, and acute-phase proteins, which mediate the inflammatory process by preventing further tissue damage and ultimately resulting in healing and restoration of tissue function. This review discusses the role of the inflammatory cells as well as their by-products in the mediation of inflammatory process. A brief insight into the role of natural anti-inflammatory agents is also discussed. The significance of this study is to explore further and understand the potential mechanism of inflammatory processes to take full advantage of vast and advanced anti-inflammatory therapies. This review aimed to reemphasize the importance on the knowledge of inflammatory processes with the addition of newest and current issues pertaining to this phenomenon.
first_indexed 2024-03-06T10:12:32Z
format Article
id upm.eprints-74127
institution Universiti Putra Malaysia
language English
last_indexed 2024-03-06T10:12:32Z
publishDate 2018
publisher Veterinary World
record_format dspace
spelling upm.eprints-741272020-04-26T19:32:13Z http://psasir.upm.edu.my/id/eprint/74127/ The crucial roles of inflammatory mediators in inflammation: a review Abdulkhaleq, Layth Abdulmajeed Assi, Mohammed Abdulrazzaq Abdullah, Rasedee Saad, M. Zamri Mohd Noor, Mohd Hezmee Yap, Taufiq Yun Hin The inflammatory response is a crucial aspect of the tissues’ responses to deleterious inflammogens. This complex response involves leukocytes cells such as macrophages, neutrophils, and lymphocytes, also known as inflammatory cells. In response to the inflammatory process, these cells release specialized substances which include vasoactive amines and peptides, eicosanoids, proinflammatory cytokines, and acute-phase proteins, which mediate the inflammatory process by preventing further tissue damage and ultimately resulting in healing and restoration of tissue function. This review discusses the role of the inflammatory cells as well as their by-products in the mediation of inflammatory process. A brief insight into the role of natural anti-inflammatory agents is also discussed. The significance of this study is to explore further and understand the potential mechanism of inflammatory processes to take full advantage of vast and advanced anti-inflammatory therapies. This review aimed to reemphasize the importance on the knowledge of inflammatory processes with the addition of newest and current issues pertaining to this phenomenon. Veterinary World 2018 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/74127/1/The%20crucial%20roles%20of%20inflammatory%20mediators%20in%20inflammation%20a%20review.pdf Abdulkhaleq, Layth Abdulmajeed and Assi, Mohammed Abdulrazzaq and Abdullah, Rasedee and Saad, M. Zamri and Mohd Noor, Mohd Hezmee and Yap, Taufiq Yun Hin (2018) The crucial roles of inflammatory mediators in inflammation: a review. Veterinary World, 11 (5). 627 - 635. ISSN 0972-8988; ESSN: 2231-0916 http://www.veterinaryworld.org/ 10.14202/vetworld.2018.627-635
spellingShingle Abdulkhaleq, Layth Abdulmajeed
Assi, Mohammed Abdulrazzaq
Abdullah, Rasedee
Saad, M. Zamri
Mohd Noor, Mohd Hezmee
Yap, Taufiq Yun Hin
The crucial roles of inflammatory mediators in inflammation: a review
title The crucial roles of inflammatory mediators in inflammation: a review
title_full The crucial roles of inflammatory mediators in inflammation: a review
title_fullStr The crucial roles of inflammatory mediators in inflammation: a review
title_full_unstemmed The crucial roles of inflammatory mediators in inflammation: a review
title_short The crucial roles of inflammatory mediators in inflammation: a review
title_sort crucial roles of inflammatory mediators in inflammation a review
url http://psasir.upm.edu.my/id/eprint/74127/1/The%20crucial%20roles%20of%20inflammatory%20mediators%20in%20inflammation%20a%20review.pdf
work_keys_str_mv AT abdulkhaleqlaythabdulmajeed thecrucialrolesofinflammatorymediatorsininflammationareview
AT assimohammedabdulrazzaq thecrucialrolesofinflammatorymediatorsininflammationareview
AT abdullahrasedee thecrucialrolesofinflammatorymediatorsininflammationareview
AT saadmzamri thecrucialrolesofinflammatorymediatorsininflammationareview
AT mohdnoormohdhezmee thecrucialrolesofinflammatorymediatorsininflammationareview
AT yaptaufiqyunhin thecrucialrolesofinflammatorymediatorsininflammationareview
AT abdulkhaleqlaythabdulmajeed crucialrolesofinflammatorymediatorsininflammationareview
AT assimohammedabdulrazzaq crucialrolesofinflammatorymediatorsininflammationareview
AT abdullahrasedee crucialrolesofinflammatorymediatorsininflammationareview
AT saadmzamri crucialrolesofinflammatorymediatorsininflammationareview
AT mohdnoormohdhezmee crucialrolesofinflammatorymediatorsininflammationareview
AT yaptaufiqyunhin crucialrolesofinflammatorymediatorsininflammationareview