In vitro and in silico evaluations of diarylpentanoid series as a-glucosidase inhibitor
A series of thirty-four diarylpentanoids derivatives were synthesized and evaluated for their α-glucosidase inhibitory activity. Eleven compounds (19, 20, 21, 24, 27, 28, 29, 31, 32, 33 and 34) were found to significantly inhibit α-glucosidase in which compounds 28, 31 and 32 demonstrated the highes...
Main Authors: | Leong, Sze Wei, Abas, Faridah, Lam, Kok Wai, Yusoff, Khatijah |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018
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Online Access: | http://psasir.upm.edu.my/id/eprint/74616/1/In%20vitro%20and%20in%20silico.pdf |
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