The effect of topical application of Malaysian honey on burn wound healing
The efficacy of topical application of Malaysian honey on burn wound healing in Sprague-Dawley rats was investigated using 45 Sprague Dawley male rats weighing 200-300 g. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honey (durian and Gelam) w...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Veterinary Association Malaysia
2004
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/7777/1/90.%207777.pdf |
| _version_ | 1796967396001447936 |
|---|---|
| author | Mohd Zohdi, Rozaini Abu Bakar @ Zakaria, Md Zuki Mohamed Mustapha, Noordin Yusof, Norimah Abdullah, Muhammad Nazrul Hakim |
| author_facet | Mohd Zohdi, Rozaini Abu Bakar @ Zakaria, Md Zuki Mohamed Mustapha, Noordin Yusof, Norimah Abdullah, Muhammad Nazrul Hakim |
| author_sort | Mohd Zohdi, Rozaini |
| collection | UPM |
| description | The efficacy of topical application of Malaysian honey on burn wound healing in Sprague-Dawley rats was investigated using 45 Sprague Dawley male rats weighing 200-300 g. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honey (durian and Gelam) were applied twice a day in a quantity of 0.5 ml for each application, while control animals received no treatment. The rats were serially euthanisised at 3, 7, 14, 21 and 28 days post treatment for histological study. Histologically, early attenuation of inflammatory reaction and early reparative activities were observed in the honey treated wounds compared to control groups. Differential cells count showed a significant decreased in the number of inflammatory cells and increased vascularity in the honey treated wounds as early as 3 days post injury. In addition, epithelial regeneration appeared to be significant in gelam honey treated wound. This study showed that there was a significant acceleration of dermal repair in wound healing treated with durian and Gelam honey. |
| first_indexed | 2024-03-06T07:13:14Z |
| format | Article |
| id | upm.eprints-7777 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T07:13:14Z |
| publishDate | 2004 |
| publisher | Veterinary Association Malaysia |
| record_format | dspace |
| spelling | upm.eprints-77772016-11-18T04:28:36Z http://psasir.upm.edu.my/id/eprint/7777/ The effect of topical application of Malaysian honey on burn wound healing Mohd Zohdi, Rozaini Abu Bakar @ Zakaria, Md Zuki Mohamed Mustapha, Noordin Yusof, Norimah Abdullah, Muhammad Nazrul Hakim The efficacy of topical application of Malaysian honey on burn wound healing in Sprague-Dawley rats was investigated using 45 Sprague Dawley male rats weighing 200-300 g. Deep partial skin thickness burns were inflicted on the dorsal part of each animal. Two types of local honey (durian and Gelam) were applied twice a day in a quantity of 0.5 ml for each application, while control animals received no treatment. The rats were serially euthanisised at 3, 7, 14, 21 and 28 days post treatment for histological study. Histologically, early attenuation of inflammatory reaction and early reparative activities were observed in the honey treated wounds compared to control groups. Differential cells count showed a significant decreased in the number of inflammatory cells and increased vascularity in the honey treated wounds as early as 3 days post injury. In addition, epithelial regeneration appeared to be significant in gelam honey treated wound. This study showed that there was a significant acceleration of dermal repair in wound healing treated with durian and Gelam honey. Veterinary Association Malaysia 2004-06 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/7777/1/90.%207777.pdf Mohd Zohdi, Rozaini and Abu Bakar @ Zakaria, Md Zuki and Mohamed Mustapha, Noordin and Yusof, Norimah and Abdullah, Muhammad Nazrul Hakim (2004) The effect of topical application of Malaysian honey on burn wound healing. Jurnal Veterinar Malaysia, 16 (1&2). pp. 47-50. ISSN 9128-2506 |
| spellingShingle | Mohd Zohdi, Rozaini Abu Bakar @ Zakaria, Md Zuki Mohamed Mustapha, Noordin Yusof, Norimah Abdullah, Muhammad Nazrul Hakim The effect of topical application of Malaysian honey on burn wound healing |
| title | The effect of topical application of Malaysian honey on burn wound healing |
| title_full | The effect of topical application of Malaysian honey on burn wound healing |
| title_fullStr | The effect of topical application of Malaysian honey on burn wound healing |
| title_full_unstemmed | The effect of topical application of Malaysian honey on burn wound healing |
| title_short | The effect of topical application of Malaysian honey on burn wound healing |
| title_sort | effect of topical application of malaysian honey on burn wound healing |
| url | http://psasir.upm.edu.my/id/eprint/7777/1/90.%207777.pdf |
| work_keys_str_mv | AT mohdzohdirozaini theeffectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT abubakarzakariamdzuki theeffectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT mohamedmustaphanoordin theeffectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT yusofnorimah theeffectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT abdullahmuhammadnazrulhakim theeffectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT mohdzohdirozaini effectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT abubakarzakariamdzuki effectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT mohamedmustaphanoordin effectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT yusofnorimah effectoftopicalapplicationofmalaysianhoneyonburnwoundhealing AT abdullahmuhammadnazrulhakim effectoftopicalapplicationofmalaysianhoneyonburnwoundhealing |