Phorbol esters from Jatropha meal triggered apoptosis, activated PKC-δ, Caspase-3 proteins and down-regulated the proto-oncogenes in MCF-7 and HeLa cancer cell lines
Jatropha meal produced from the kernel of Jatropha curcas Linn. grown in Malaysia contains phorbol esters (PEs). The potential benefits of PEs present in the meal as anticancer agent are still not well understood. Hence, this study was conducted to evaluate the cytotoxic effects and mode of actions...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI
2012
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| Online Access: | http://psasir.upm.edu.my/id/eprint/78015/1/78015.pdf |