Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome

Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome

Notch signalling pathway is involved in the proliferation of neural progenitor cells (NPCs), to inhibit neuronal cell commitment and to promote glial cell fate. Notch protein is cleaved by gamma-secretase, a multisubunit transmembrane protein complex that releases the Notch intracellular domain (NIC...

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Bibliographic Details
Main Authors:	Md Yusof, Hadri Hadi, Lee, Han Chung, Mohamed Seth, Eryse Amira, Wu, Xiangzhong, Hewitt, Chelsee A., Scott, Hamish S., Cheah, Pike See, Li, Yue Ming, Chau, De Ming, Ling, King Hwa
Format:	Article
Published:	Springer 2019

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