In vitro evidence consistent with an interaction between wild‐type and mutant SOD1 protein associated with canine degenerative myelopathy

Canine degenerative myelopathy (DM) is a progressive neurological disorder that may be considered to be a large animal model for specific forms of the fatal human disease, familial amyotrophic lateral sclerosis (fALS). DM is associated with a c118G>A mutation of the superoxide dismutase 1 (Sod1)...

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Bibliographic Details
Main Authors: Qi, Yao, Montague, Paul, Loney, Colin, Campbell, Clare, Shafie, Intan Nur Fatiha, Anderson, Thomes J., Mclaughlin, Mark
Format: Article
Language:English
Published: Wiley-Blackwell Publishing 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80224/1/In%20vitro%20evidence%20consistent%20with%20an%20interaction%20between%20wild%E2%80%90type%20and%20mutant%20SOD1%20protein%20associated%20with%20canine%20degenerative%20myelopathy.pdf