Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus)
Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg....
| Hoofdauteurs: | , , , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
Japanese Society of Veterinary Science
2019
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| Online toegang: | http://psasir.upm.edu.my/id/eprint/80978/1/ALFAZALONE.pdf |
| _version_ | 1825951366680412160 |
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| author | Ahmad, Ali Anwar Abd Wahab, Norsham Yeo, Wenjing Clara Yin, Serena Jocelyn Oh Wai Chen, Hui Cheng |
| author_facet | Ahmad, Ali Anwar Abd Wahab, Norsham Yeo, Wenjing Clara Yin, Serena Jocelyn Oh Wai Chen, Hui Cheng |
| author_sort | Ahmad, Ali Anwar |
| collection | UPM |
| description | Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination. |
| first_indexed | 2024-03-06T10:28:56Z |
| format | Article |
| id | upm.eprints-80978 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:28:56Z |
| publishDate | 2019 |
| publisher | Japanese Society of Veterinary Science |
| record_format | dspace |
| spelling | upm.eprints-809782020-10-14T20:37:43Z http://psasir.upm.edu.my/id/eprint/80978/ Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) Ahmad, Ali Anwar Abd Wahab, Norsham Yeo, Wenjing Clara Yin, Serena Jocelyn Oh Wai Chen, Hui Cheng Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination. Japanese Society of Veterinary Science 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/80978/1/ALFAZALONE.pdf Ahmad, Ali Anwar and Abd Wahab, Norsham and Yeo, Wenjing Clara and Yin, Serena Jocelyn Oh Wai and Chen, Hui Cheng (2019) Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus). Journal of Veterinary Medical Science, 81 (1). pp. 48-52. ISSN 0916-7250; ESSN: 1347-7439 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361648/ 10.1292/jvms.18-0297 |
| spellingShingle | Ahmad, Ali Anwar Abd Wahab, Norsham Yeo, Wenjing Clara Yin, Serena Jocelyn Oh Wai Chen, Hui Cheng Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title_full | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title_fullStr | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title_full_unstemmed | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title_short | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
| title_sort | comparison of alfaxalone medetomidine and tiletamine zolazepam in rescued common palm civets paradoxurus musangus |
| url | http://psasir.upm.edu.my/id/eprint/80978/1/ALFAZALONE.pdf |
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