Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells

Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells

Mast cells (MCs), a type of immune effector cell, have recently become recognized for their ability to cause vascular leakage during dengue virus (DENV) infection. Although MC stabilizers have been reported to attenuate DENV induced infection in animal studies, there are limited in vitro studies on...

Full description

Bibliographic Details
Main Authors:	Tan, Ji Wei, Wan Zahidi, Nuha Fahimah, Siew, Audrey Foong Kow, Soo, Kuan Meng, Shaari, Khozirah, Ahmad Israf, Daud, Chee, Hui Yee, Tham, Chau Ling
Format:	Article
Language:	English
Published:	Portland Press 2019
Online Access:	http://psasir.upm.edu.my/id/eprint/81291/1/CELL.pdf

Similar Items

Pharmacological properties of 2,4,6-Trihydroxy-3-geranyl acetophenone and the underlying signaling pathways: progress and prospects
by: Chan, Yee Han, et al.
Published: (2021)

Regulation of ige-mediated mast cell degranulation in allergy by geranyl acetophenone
by: Tan, Ji Wei
Published: (2017)

Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells
by: Yi, Joong Chong, et al.
Published: (2016)

Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells
by: Chong, Yi Joong, et al.
Published: (2016)

Blockade of eosinophil-induced bronchial epithelial-mesenchymal transition with a geranyl acetophenone in a coculture model
by: Lee, Yu Zhao, et al.
Published: (2017)

The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation
by: Yap, Hui Min, et al.
Published: (2018)

The protective effects of a synthetic geranyl acetophenone in a cellular model of TNF-α-induced pulmonary epithelial barrier dysfunction
by: Tee, Yee Sim, et al.
Published: (2018)

Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice
by: Mohd Kasim, Vivi Nur Khalieda, et al.
Published: (2024)

Oral and topical administration of a geranyl acetophenone attenuates DNCB‑induced atopic dermatitis‑like skin lesions in BALB/c mice
by: Mohd Kasim, Vivi Nur Khalieda, et al.
Published: (2024)

Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice
by: Vivi Nur Khalieda Mohd Kasim, et al.
Published: (2024-07-01)

Airway remodeling blockade with an orally active geranyl acetophenone
by: Lee, Yu Zhao
Published: (2017)

Author Correction: Oral and topical administration of a geranyl acetophenone attenuates DNCB-induced atopic dermatitis-like skin lesions in BALB/c mice
by: Vivi Nur Khalieda Mohd Kasim, et al.
Published: (2024-10-01)

RBL-2H3 Mast Cell Receptor Dynamics in the Immunological Synapse
by: Ming Chih Tsai, et al.
Published: (2022-11-01)

2, 4, 6,-trihydroxy- 3-geranylacetophenone (tHGA) inhibits newly synthesized mediators release in IgE-mediated mast cell degranulation
by: Tan, Ji Wei, et al.
Published: (2015)

Oral administration of a potential mast cell stabilizer, tHGA, prevents IgE-mediated anaphylaxis in rats
by: Tan, Ji Wei, et al.
Published: (2016)

LAT is essential for the mast cell stabilising effect of tHGA in IgE-mediated mast cell activation
by: Tan, Ji Wei, et al.
Published: (2017)

Effects of 2,4,6-trihydroxy-3-geranyl acetophenone on growth factor-induced human bronchial smooth muscle cell proliferation in asthma
by: Yap, Hui Min
Published: (2018)

Clinacanthus nutans aqueous extract suppresses the release of histamine and β-Hexosaminidase inin-vitro model of IgE-mediated mast cell degranulation
by: Kow, Audrey Siew Foong, et al.
Published: (2020)

Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment
by: Ng, Chean Hui, et al.
Published: (2018)

Association of immunoglobulin G abnormalities in diseases: a mini review
by: Tham, Chau Ling, et al.
Published: (2018)

Myrrh and Chamomile Flower Extract Inhibit Mediator Release from IgE-stimulated Mast-Cell-Like RBL-2H3 Cells
by: Fabian Altenbernd, et al.
Published: (2022-12-01)

In vitro protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on junctional protein disruption and the underlying signaling pathways in lipopolysaccharide-induced endothelial hyperpermeability
by: Chan, Yee Han
Published: (2022)

Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis
by: Tan, Ji Wei, et al.
Published: (2017)

Antiallergic Effect of the Alpha-Cyclodextrin Moringin Complex in Rat Basophilic Leukaemia (RBL-2H3) Cell Line
by: Ebtisam Yousef A. Alnakeeb, et al.
Published: (2024-01-01)

Antiallergic effect of the alpha‐cyclodextrin Moringin complex in rat basophilic leukaemia (RBL‐2H3) cell line
by: Yousef A. Alnakeeb, Ebtisam, et al.
Published: (2024)

Effects of deuterium oxide on cell growth and vesicle speed in RBL-2H3 cells
by: Roshni S. Kalkur, et al.
Published: (2014-09-01)

Comparison of Cytotoxic and Antiproliferative Effects of Benzylidenecyclopentanone Analogues of Curcumin on RBL-2H3 Cells
by: Perpustakaan UGM, i-lib
Published: (2010)

An eco-friendly and new facile method for synthesis of prenylated or geranylated acylphloroglucinol-based xanthenones
by: Tamil Segaran, Raaginie, et al.
Published: (2024)

A phloroglucinol from Melicope ptelefolia preserves barrier integrity of lipopolysaccharide-induced endothelial cells: study on junctional proteins and cytoskeleton remodeling
by: Chong, Yi Joong, et al.
Published: (2015)

Davallia mariesii Moore Improves FcεRI-Mediated Allergic Responses in the Rat Basophilic Leukemia Mast Cell Line RBL-2H3 and Passive Cutaneous Anaphylaxis in Mice
by: Hyun Ju Do, et al.
Published: (2017-01-01)

Inhibitory Effect of Methyleugenol on IgE-Mediated Allergic Inflammation in RBL-2H3 Cells
by: Feng Tang, et al.
Published: (2015-01-01)

Clinacanthus nutans aqueous extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway
by: Kow, Audrey Siew Foong, et al.
Published: (2023)

Anti-DENV-ED3 antibody cross-talks generate immune interference among the four DENVs
by: Md. Din Islam, et al.
Published: (2024-12-01)

Thapsigargin induces non-apoptotic programmed cell death in RBL-1 cells
by: Steiner Philip, et al.
Published: (2024-01-01)

Inhibitory Effect of Dipeptides Containing Acidic Amino Acid Residue on Degranulation of RBL-2H3 Cells
by: Kosuke Nishi, et al.
Published: (2024-08-01)

Inhibitory Effect of Loranthus parasiticus on IgE-Mediated Allergic Responses in RBL-2H3 Cells
by: Jae-Myung Yoo, et al.
Published: (2016-01-01)

Inhibitory effect of THPGV-O on the histamine release from antigen-induced RBL-2H3 cells Efek THPGV-O terhadap pelepasan histamin dari kultur sel RBL-2H3 diinduksi antigen
by: Perpustakaan UGM, i-lib
Published: (2010)

Time-sensitive effects of quercetin on rat basophilic leukemia (RBL-2H3) cell responsiveness and intracellular signaling.
by: Mana Matsuo, et al.
Published: (2025-01-01)

Screening and Identification of Probiotics with in Vitro Anti-Allergic Activity Based on the Degranulation Inhibition of RBL-2H3 Cells
by: Ma Ding, Qin Shuangxia, Hao Huichao, Deng Fangming, Zhao Lingyan
Published: (2024-03-01)

Comparative monocyte and T cell responses in DENV-exposed subjects from South-East Asia and DENV-naïve residents in Taiwan
by: Sheng-Hsuan Wang, et al.
Published: (2025-02-01)