Nanomedicines for cancer therapy: current status, challenges and future prospects
The emergence of nanomedicine as an innovative and promising alternative technology shows many advantages over conventional cancer therapies and provides new opportunities for early detection, improved treatment, and diagnosis of cancer. Despite the cancer nanomedicines' capability of deliverin...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Future Science
2019
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/81452/1/Nanomedicines%20for%20cancer%20therapy%20current%20status%2C%20challenges%20and%20future%20prospects.pdf |
| _version_ | 1825951442260721664 |
|---|---|
| author | Bor, Gizem Mat Azmi, Intan Diana Yaghmur, Anan |
| author_facet | Bor, Gizem Mat Azmi, Intan Diana Yaghmur, Anan |
| author_sort | Bor, Gizem |
| collection | UPM |
| description | The emergence of nanomedicine as an innovative and promising alternative technology shows many advantages over conventional cancer therapies and provides new opportunities for early detection, improved treatment, and diagnosis of cancer. Despite the cancer nanomedicines' capability of delivering chemotherapeutic agents while providing lower systemic toxicity, it is paramount to consider the cancer complexity and dynamics for bridging the translational bench-to-bedside gap. It is important to conduct appropriate investigations for exploiting the tumor microenvironment, and achieving a more comprehensive understanding of the fundamental biological processes in cancer and their roles in modulating nanoparticle-protein interactions, blood circulation, and tumor penetration. This review provides an overview of the current cancer nanomedicines, the major challenges, and the future opportunities in this research area. |
| first_indexed | 2024-03-06T10:30:05Z |
| format | Article |
| id | upm.eprints-81452 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:30:05Z |
| publishDate | 2019 |
| publisher | Future Science |
| record_format | dspace |
| spelling | upm.eprints-814522021-01-31T14:48:54Z http://psasir.upm.edu.my/id/eprint/81452/ Nanomedicines for cancer therapy: current status, challenges and future prospects Bor, Gizem Mat Azmi, Intan Diana Yaghmur, Anan The emergence of nanomedicine as an innovative and promising alternative technology shows many advantages over conventional cancer therapies and provides new opportunities for early detection, improved treatment, and diagnosis of cancer. Despite the cancer nanomedicines' capability of delivering chemotherapeutic agents while providing lower systemic toxicity, it is paramount to consider the cancer complexity and dynamics for bridging the translational bench-to-bedside gap. It is important to conduct appropriate investigations for exploiting the tumor microenvironment, and achieving a more comprehensive understanding of the fundamental biological processes in cancer and their roles in modulating nanoparticle-protein interactions, blood circulation, and tumor penetration. This review provides an overview of the current cancer nanomedicines, the major challenges, and the future opportunities in this research area. Future Science 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81452/1/Nanomedicines%20for%20cancer%20therapy%20current%20status%2C%20challenges%20and%20future%20prospects.pdf Bor, Gizem and Mat Azmi, Intan Diana and Yaghmur, Anan (2019) Nanomedicines for cancer therapy: current status, challenges and future prospects. Therapeutic delivery, 10 (2). pp. 113-132. ISSN 2041-5990; ESSN: 2041-6008 https://pubmed.ncbi.nlm.nih.gov/30678550/ 10.4155/tde-2018-0062 |
| spellingShingle | Bor, Gizem Mat Azmi, Intan Diana Yaghmur, Anan Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title | Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title_full | Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title_fullStr | Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title_full_unstemmed | Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title_short | Nanomedicines for cancer therapy: current status, challenges and future prospects |
| title_sort | nanomedicines for cancer therapy current status challenges and future prospects |
| url | http://psasir.upm.edu.my/id/eprint/81452/1/Nanomedicines%20for%20cancer%20therapy%20current%20status%2C%20challenges%20and%20future%20prospects.pdf |
| work_keys_str_mv | AT borgizem nanomedicinesforcancertherapycurrentstatuschallengesandfutureprospects AT matazmiintandiana nanomedicinesforcancertherapycurrentstatuschallengesandfutureprospects AT yaghmuranan nanomedicinesforcancertherapycurrentstatuschallengesandfutureprospects |