Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review
Acute renal cortical necrosis (ACN) is a potentially fatal renal condition. Our objective is to report a case of ACN in a young man who had developed premature atherosclerotic vascular disease and required intermittent hemodialysis support. His renal biopsy showed diffuse cortical necrosis. Subseque...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medknow Publications (India)
2019
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| Online Access: | http://psasir.upm.edu.my/id/eprint/81616/1/Partially%20reversible%20acute%20renal%20cortical%20necrosis%20secondary%20to%20hyperhomocysteinemia%20-%20a%20case%20report%20and%20literature%20review.pdf |
| _version_ | 1825951469547814912 |
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| author | Tan, Wendy Abd Ghani, Fauzah Lim, Christopher Thiam Seong |
| author_facet | Tan, Wendy Abd Ghani, Fauzah Lim, Christopher Thiam Seong |
| author_sort | Tan, Wendy |
| collection | UPM |
| description | Acute renal cortical necrosis (ACN) is a potentially fatal renal condition. Our objective is to report a case of ACN in a young man who had developed premature atherosclerotic vascular disease and required intermittent hemodialysis support. His renal biopsy showed diffuse cortical necrosis. Subsequently, 2 weeks after the renal insult, he developed a cardioembolic stroke and was anticoagulated with low-molecular-weight heparin. Thrombophilia screen revealed elevated serum homocystein and he was treated with folate supplement and vitamin B12 injection. With these treatments, he had partial renal recovery and became dialysis independent. In conclusion, this is a rare case of ACN, which may have occurred as a complication of hyperhomocysteinemia. |
| first_indexed | 2024-03-06T10:30:29Z |
| format | Article |
| id | upm.eprints-81616 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:30:29Z |
| publishDate | 2019 |
| publisher | Medknow Publications (India) |
| record_format | dspace |
| spelling | upm.eprints-816162020-11-02T17:50:08Z http://psasir.upm.edu.my/id/eprint/81616/ Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review Tan, Wendy Abd Ghani, Fauzah Lim, Christopher Thiam Seong Acute renal cortical necrosis (ACN) is a potentially fatal renal condition. Our objective is to report a case of ACN in a young man who had developed premature atherosclerotic vascular disease and required intermittent hemodialysis support. His renal biopsy showed diffuse cortical necrosis. Subsequently, 2 weeks after the renal insult, he developed a cardioembolic stroke and was anticoagulated with low-molecular-weight heparin. Thrombophilia screen revealed elevated serum homocystein and he was treated with folate supplement and vitamin B12 injection. With these treatments, he had partial renal recovery and became dialysis independent. In conclusion, this is a rare case of ACN, which may have occurred as a complication of hyperhomocysteinemia. Medknow Publications (India) 2019 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/81616/1/Partially%20reversible%20acute%20renal%20cortical%20necrosis%20secondary%20to%20hyperhomocysteinemia%20-%20a%20case%20report%20and%20literature%20review.pdf Tan, Wendy and Abd Ghani, Fauzah and Lim, Christopher Thiam Seong (2019) Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review. Indian Journal of Nephrology, 29 (4). pp. 288-290. ISSN 0971-4065; ESSN: 1998-3662 https://www.indianjnephrol.org/article.asp?issn=0971-4065;year=2019;volume=29;issue=4;spage=288;epage=290;aulast=Tan 10.4103/ijn.IJN_153_18 |
| spellingShingle | Tan, Wendy Abd Ghani, Fauzah Lim, Christopher Thiam Seong Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title | Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title_full | Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title_fullStr | Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title_full_unstemmed | Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title_short | Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review |
| title_sort | partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia a case report and literature review |
| url | http://psasir.upm.edu.my/id/eprint/81616/1/Partially%20reversible%20acute%20renal%20cortical%20necrosis%20secondary%20to%20hyperhomocysteinemia%20-%20a%20case%20report%20and%20literature%20review.pdf |
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