Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: an updated review

Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: an updated review

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5-fluorouracil (5-FU) refers to a fluorinated pyrimidine analogue that has been widely used as an anticancer agent for colon, head, and neck cancers. Detection of 5-FU and its metabolites; 5-fluorouridine and 5-fluoro-2-deoxyuridine in biological samples allows optimization of pharmacotherapy and en...

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Bibliographic Details
Main Authors: Semail, Nadhiratul farihin, Abdul Keyon, Aemi Syazwani, Saad, Bahruddin, Noordin, Siti Salmah, Nik Mohamed Kamal, Nik Nur Syazni, Mohamad Zain, Nur Nadhirah, Azizi, Juzaili, Kamaruzaman, Sazlinda, Yahaya, Noorfatimah
Format: Article
Language:English
Published: Taylor and Francis 2020
Online Access:http://psasir.upm.edu.my/id/eprint/87877/1/ABSTRACT.pdf

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