Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2)
The aim of this study was to identify the bioactive compound and evaluate the antibacterial activity of torch ginger flower oil extracted using subcritical carbon dioxide. The antibacterial activity was evaluated in agar diffusion assay, while MIC and MBC were determined using the microdilution brot...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Publishing
2020
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/87883/1/ABSTRACT.pdf |
| _version_ | 1796981901881245696 |
|---|---|
| author | Anzian, Aliaa Muhialdin, Belal J. Mohammed, Nameer Khairullah Kadum, Hana Marzlan, Anis Asyila Sukor, Rashidah Meor Hussin, Anis Shobirin |
| author_facet | Anzian, Aliaa Muhialdin, Belal J. Mohammed, Nameer Khairullah Kadum, Hana Marzlan, Anis Asyila Sukor, Rashidah Meor Hussin, Anis Shobirin |
| author_sort | Anzian, Aliaa |
| collection | UPM |
| description | The aim of this study was to identify the bioactive compound and evaluate the antibacterial activity of torch ginger flower oil extracted using subcritical carbon dioxide. The antibacterial activity was evaluated in agar diffusion assay, while MIC and MBC were determined using the microdilution broth assay. The essential oil was subjected to metabolomics profiling using GC-MS and 1H-NMR techniques. The results demonstrated strong antibacterial activity towards Salmonella typhimurium, Staphylococcus aureus, and Escherichia coli. The MIC values were 0.0625, 0.25, and 0.25 mg/mL, and the MBC values were 0.25, 0.5, and 1 mg/mL towards S. typhimurium, S. aureus, and E. coli, respectively. A total of 33 compounds were identified using GC-MS including 15 compounds (45%) known for their antimicrobial activity. In addition, sixteen metabolites were identified using NMR analysis and 8 out of the sixteen metabolites (50%) have antibacterial activity. The extracted oil demonstrated broad range for antibacterial activity and has high potential for applications in pharmaceutical and food industries. Practical Applications. The oil extracted from the torch ginger flower was found very stable and has promising applications as antibacterial agent for food and pharmaceutical industries. |
| first_indexed | 2024-03-06T10:44:26Z |
| format | Article |
| id | upm.eprints-87883 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:44:26Z |
| publishDate | 2020 |
| publisher | Hindawi Publishing |
| record_format | dspace |
| spelling | upm.eprints-878832022-06-07T06:44:49Z http://psasir.upm.edu.my/id/eprint/87883/ Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) Anzian, Aliaa Muhialdin, Belal J. Mohammed, Nameer Khairullah Kadum, Hana Marzlan, Anis Asyila Sukor, Rashidah Meor Hussin, Anis Shobirin The aim of this study was to identify the bioactive compound and evaluate the antibacterial activity of torch ginger flower oil extracted using subcritical carbon dioxide. The antibacterial activity was evaluated in agar diffusion assay, while MIC and MBC were determined using the microdilution broth assay. The essential oil was subjected to metabolomics profiling using GC-MS and 1H-NMR techniques. The results demonstrated strong antibacterial activity towards Salmonella typhimurium, Staphylococcus aureus, and Escherichia coli. The MIC values were 0.0625, 0.25, and 0.25 mg/mL, and the MBC values were 0.25, 0.5, and 1 mg/mL towards S. typhimurium, S. aureus, and E. coli, respectively. A total of 33 compounds were identified using GC-MS including 15 compounds (45%) known for their antimicrobial activity. In addition, sixteen metabolites were identified using NMR analysis and 8 out of the sixteen metabolites (50%) have antibacterial activity. The extracted oil demonstrated broad range for antibacterial activity and has high potential for applications in pharmaceutical and food industries. Practical Applications. The oil extracted from the torch ginger flower was found very stable and has promising applications as antibacterial agent for food and pharmaceutical industries. Hindawi Publishing 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/87883/1/ABSTRACT.pdf Anzian, Aliaa and Muhialdin, Belal J. and Mohammed, Nameer Khairullah and Kadum, Hana and Marzlan, Anis Asyila and Sukor, Rashidah and Meor Hussin, Anis Shobirin (2020) Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2). Evidence-based Complementary and Alternative Medicine, 2020. pp. 1-8. ISSN 1741-427X; ESSN: 1741-4288 https://www.hindawi.com/journals/ecam/2020/4373401/ 10.1155/2020/4373401 |
| spellingShingle | Anzian, Aliaa Muhialdin, Belal J. Mohammed, Nameer Khairullah Kadum, Hana Marzlan, Anis Asyila Sukor, Rashidah Meor Hussin, Anis Shobirin Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title | Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title_full | Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title_fullStr | Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title_full_unstemmed | Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title_short | Antibacterial activity and metabolomics profiling of torch ginger (Etlingera elatior Jack) flower oil extracted using subcritical carbon dioxide (CO2) |
| title_sort | antibacterial activity and metabolomics profiling of torch ginger etlingera elatior jack flower oil extracted using subcritical carbon dioxide co2 |
| url | http://psasir.upm.edu.my/id/eprint/87883/1/ABSTRACT.pdf |
| work_keys_str_mv | AT anzianaliaa antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT muhialdinbelalj antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT mohammednameerkhairullah antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT kadumhana antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT marzlananisasyila antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT sukorrashidah antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 AT meorhussinanisshobirin antibacterialactivityandmetabolomicsprofilingoftorchgingeretlingeraelatiorjackfloweroilextractedusingsubcriticalcarbondioxideco2 |