Canine parvovirus (CPV) infection in a great dane puppy: a case report

Canine parvovirus (CPV) infection is a major disease affecting young pups with high contagiousness and mortality worldwide. Unvaccinated pups between 6 weeks to 6 months are most susceptible to CPV infection. It manifests into enteritis and myocarditis forms. Classical signs of enteritis form includ...

Full description

Bibliographic Details
Main Authors: Raslan, Nurul Ain, Saulol Hamid, Nur Fazila, Abdul Rahaman, Yasmin, Abd Rahaman, Noor Sifa Shaida, Wan Noor, Wan Nur Ayuni, Zakaria, Muhamad Alif
Format: Article
Language:English
Published: Nexus Academic Publishers 2020
Online Access:http://psasir.upm.edu.my/id/eprint/88080/1/ABSTRACT.pdf
_version_ 1825952446773460992
author Raslan, Nurul Ain
Saulol Hamid, Nur Fazila
Abdul Rahaman, Yasmin
Abd Rahaman, Noor Sifa Shaida
Wan Noor, Wan Nur Ayuni
Zakaria, Muhamad Alif
author_facet Raslan, Nurul Ain
Saulol Hamid, Nur Fazila
Abdul Rahaman, Yasmin
Abd Rahaman, Noor Sifa Shaida
Wan Noor, Wan Nur Ayuni
Zakaria, Muhamad Alif
author_sort Raslan, Nurul Ain
collection UPM
description Canine parvovirus (CPV) infection is a major disease affecting young pups with high contagiousness and mortality worldwide. Unvaccinated pups between 6 weeks to 6 months are most susceptible to CPV infection. It manifests into enteritis and myocarditis forms. Classical signs of enteritis form include acute onset of vomiting, haemorrhagic diarrhoea, and pyrexia. A case of unvaccinated 3-month-old female Great Dane puppy was presented with complaints of hematemesis, hematochezia and shooting diarrhoea. A tentative diagnosis of CPV was made. It was humanely euthanised due to chronic body weight loss and poor response to treatments. Post-mortem examinations revealed congested lung with frothy exudate, whitish plaques on heart coronary groove, thickened intestinal mucosa, and generalised reddening in the liver and kidneys. Microscopic changes revealed interstitial pneumonia with edema, lymphocytic myocarditis, viral enteritis with villous atrophy, and liver congestion. A faecal samples for polymerase chain reaction (PCR) method revealed positive result for parvovirus. Based on pathological and PCR findings, it was definitively diagnosed with CPV infection. The chance of its survival without aggressive treatment remains low. Treatment and management are still limited to supportive care without existing agent-specific treatment. Therefore, CPV infection should be controlled and prevented by providing vaccination to the pups from the age of 6 weeks.
first_indexed 2024-03-06T10:44:46Z
format Article
id upm.eprints-88080
institution Universiti Putra Malaysia
language English
last_indexed 2024-03-06T10:44:46Z
publishDate 2020
publisher Nexus Academic Publishers
record_format dspace
spelling upm.eprints-880802022-05-18T04:11:55Z http://psasir.upm.edu.my/id/eprint/88080/ Canine parvovirus (CPV) infection in a great dane puppy: a case report Raslan, Nurul Ain Saulol Hamid, Nur Fazila Abdul Rahaman, Yasmin Abd Rahaman, Noor Sifa Shaida Wan Noor, Wan Nur Ayuni Zakaria, Muhamad Alif Canine parvovirus (CPV) infection is a major disease affecting young pups with high contagiousness and mortality worldwide. Unvaccinated pups between 6 weeks to 6 months are most susceptible to CPV infection. It manifests into enteritis and myocarditis forms. Classical signs of enteritis form include acute onset of vomiting, haemorrhagic diarrhoea, and pyrexia. A case of unvaccinated 3-month-old female Great Dane puppy was presented with complaints of hematemesis, hematochezia and shooting diarrhoea. A tentative diagnosis of CPV was made. It was humanely euthanised due to chronic body weight loss and poor response to treatments. Post-mortem examinations revealed congested lung with frothy exudate, whitish plaques on heart coronary groove, thickened intestinal mucosa, and generalised reddening in the liver and kidneys. Microscopic changes revealed interstitial pneumonia with edema, lymphocytic myocarditis, viral enteritis with villous atrophy, and liver congestion. A faecal samples for polymerase chain reaction (PCR) method revealed positive result for parvovirus. Based on pathological and PCR findings, it was definitively diagnosed with CPV infection. The chance of its survival without aggressive treatment remains low. Treatment and management are still limited to supportive care without existing agent-specific treatment. Therefore, CPV infection should be controlled and prevented by providing vaccination to the pups from the age of 6 weeks. Nexus Academic Publishers 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88080/1/ABSTRACT.pdf Raslan, Nurul Ain and Saulol Hamid, Nur Fazila and Abdul Rahaman, Yasmin and Abd Rahaman, Noor Sifa Shaida and Wan Noor, Wan Nur Ayuni and Zakaria, Muhamad Alif (2020) Canine parvovirus (CPV) infection in a great dane puppy: a case report. Advances in Animal and Veterinary Sciences, 8 (10). 1075 - 1078. ISSN 2309-3331; ESSN: 2307-8316 https://nexusacademicpublishers.com/table_contents_detail/4/1526 10.17582/journal.aavs/2020/8.10.1075.1078
spellingShingle Raslan, Nurul Ain
Saulol Hamid, Nur Fazila
Abdul Rahaman, Yasmin
Abd Rahaman, Noor Sifa Shaida
Wan Noor, Wan Nur Ayuni
Zakaria, Muhamad Alif
Canine parvovirus (CPV) infection in a great dane puppy: a case report
title Canine parvovirus (CPV) infection in a great dane puppy: a case report
title_full Canine parvovirus (CPV) infection in a great dane puppy: a case report
title_fullStr Canine parvovirus (CPV) infection in a great dane puppy: a case report
title_full_unstemmed Canine parvovirus (CPV) infection in a great dane puppy: a case report
title_short Canine parvovirus (CPV) infection in a great dane puppy: a case report
title_sort canine parvovirus cpv infection in a great dane puppy a case report
url http://psasir.upm.edu.my/id/eprint/88080/1/ABSTRACT.pdf
work_keys_str_mv AT raslannurulain canineparvoviruscpvinfectioninagreatdanepuppyacasereport
AT saulolhamidnurfazila canineparvoviruscpvinfectioninagreatdanepuppyacasereport
AT abdulrahamanyasmin canineparvoviruscpvinfectioninagreatdanepuppyacasereport
AT abdrahamannoorsifashaida canineparvoviruscpvinfectioninagreatdanepuppyacasereport
AT wannoorwannurayuni canineparvoviruscpvinfectioninagreatdanepuppyacasereport
AT zakariamuhamadalif canineparvoviruscpvinfectioninagreatdanepuppyacasereport