Carcinosarcoma of the maxillary sinus: a rare case report

Carcinosarcoma is a highly malignant tumour exhibiting histological components of both carcinomatous and sarcomatoid elements. Carcinosarcoma is extremely rare in the sinonasal cavity. Due to the rarity and clinical diversity, these neoplasms are often misdiagnosed and pose a challenge in their man...

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Main Authors: Subha, Sethu Thakachy, Doi, Mohamad, Mohd Yatim, Nor Yatizah
Format: Article
Language:English
Published: Iranian Pediatric Hematology and Oncology Society 2020
Online Access:http://psasir.upm.edu.my/id/eprint/88089/1/ABSTRACT.pdf
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author Subha, Sethu Thakachy
Doi, Mohamad
Mohd Yatim, Nor Yatizah
author_facet Subha, Sethu Thakachy
Doi, Mohamad
Mohd Yatim, Nor Yatizah
author_sort Subha, Sethu Thakachy
collection UPM
description Carcinosarcoma is a highly malignant tumour exhibiting histological components of both carcinomatous and sarcomatoid elements. Carcinosarcoma is extremely rare in the sinonasal cavity. Due to the rarity and clinical diversity, these neoplasms are often misdiagnosed and pose a challenge in their management. Here we report a 44-year-old man with epistaxis and progressive symptoms of nasal obstruction. Nasal endoscopy revealed a polypoid mass in right middle meatus extending into the nasal cavity. Polypectomy through endoscopic sinus surgery was performed. Carcinosarcoma was diagnosed based on histopathology and immunohistochemical studies. The patient underwent total maxillectomy followed by radiotherapy for the residual tumor. Unfortunately, the patient suffered from multiple recurrences during 20 months following primary resection. This report is to emphasize the need for early diagnosis and radical multimodality intervention for this rare malignancy with an ominous prognosis.
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spelling upm.eprints-880892022-05-18T06:38:25Z http://psasir.upm.edu.my/id/eprint/88089/ Carcinosarcoma of the maxillary sinus: a rare case report Subha, Sethu Thakachy Doi, Mohamad Mohd Yatim, Nor Yatizah Carcinosarcoma is a highly malignant tumour exhibiting histological components of both carcinomatous and sarcomatoid elements. Carcinosarcoma is extremely rare in the sinonasal cavity. Due to the rarity and clinical diversity, these neoplasms are often misdiagnosed and pose a challenge in their management. Here we report a 44-year-old man with epistaxis and progressive symptoms of nasal obstruction. Nasal endoscopy revealed a polypoid mass in right middle meatus extending into the nasal cavity. Polypectomy through endoscopic sinus surgery was performed. Carcinosarcoma was diagnosed based on histopathology and immunohistochemical studies. The patient underwent total maxillectomy followed by radiotherapy for the residual tumor. Unfortunately, the patient suffered from multiple recurrences during 20 months following primary resection. This report is to emphasize the need for early diagnosis and radical multimodality intervention for this rare malignancy with an ominous prognosis. Iranian Pediatric Hematology and Oncology Society 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88089/1/ABSTRACT.pdf Subha, Sethu Thakachy and Doi, Mohamad and Mohd Yatim, Nor Yatizah (2020) Carcinosarcoma of the maxillary sinus: a rare case report. Iranian Journal of Blood and Cancer, 12 (3). pp. 101-103. ISSN 2008-4595; ESSN: 2008-4609 https://ijbc.ir/article-1-953-en.html
spellingShingle Subha, Sethu Thakachy
Doi, Mohamad
Mohd Yatim, Nor Yatizah
Carcinosarcoma of the maxillary sinus: a rare case report
title Carcinosarcoma of the maxillary sinus: a rare case report
title_full Carcinosarcoma of the maxillary sinus: a rare case report
title_fullStr Carcinosarcoma of the maxillary sinus: a rare case report
title_full_unstemmed Carcinosarcoma of the maxillary sinus: a rare case report
title_short Carcinosarcoma of the maxillary sinus: a rare case report
title_sort carcinosarcoma of the maxillary sinus a rare case report
url http://psasir.upm.edu.my/id/eprint/88089/1/ABSTRACT.pdf
work_keys_str_mv AT subhasethuthakachy carcinosarcomaofthemaxillarysinusararecasereport
AT doimohamad carcinosarcomaofthemaxillarysinusararecasereport
AT mohdyatimnoryatizah carcinosarcomaofthemaxillarysinusararecasereport