Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells
Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomaterial is readily available and is of low cost. In addition, CACNP is highly porous, has a larg...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Springer
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/88180/1/ABSTRACT.pdf |
| _version_ | 1825952461957890048 |
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| author | Ibiyeye, Kehinde Muibat Banke, Idris Sherifat Zakaria, Md Zuki Abu Bakar |
| author_facet | Ibiyeye, Kehinde Muibat Banke, Idris Sherifat Zakaria, Md Zuki Abu Bakar |
| author_sort | Ibiyeye, Kehinde Muibat |
| collection | UPM |
| description | Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomaterial is readily available and is of low cost. In addition, CACNP is highly porous, has a large surface area which confer a high loading capacity. The pH-dependent release properties as well as its potential for surface functionalization with targeting agents make CACNP useful in passive and active targeting of cancer cells and cancer stem cells. In this article, we reviewed the current state of CACNP as nano-sized drug carrier for targeting cancer cells, cancer stem cells and its biocompatibility. |
| first_indexed | 2024-03-06T10:44:59Z |
| format | Article |
| id | upm.eprints-88180 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:44:59Z |
| publishDate | 2020 |
| publisher | Springer |
| record_format | dspace |
| spelling | upm.eprints-881802022-05-18T03:12:05Z http://psasir.upm.edu.my/id/eprint/88180/ Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells Ibiyeye, Kehinde Muibat Banke, Idris Sherifat Zakaria, Md Zuki Abu Bakar Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomaterial is readily available and is of low cost. In addition, CACNP is highly porous, has a large surface area which confer a high loading capacity. The pH-dependent release properties as well as its potential for surface functionalization with targeting agents make CACNP useful in passive and active targeting of cancer cells and cancer stem cells. In this article, we reviewed the current state of CACNP as nano-sized drug carrier for targeting cancer cells, cancer stem cells and its biocompatibility. Springer 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88180/1/ABSTRACT.pdf Ibiyeye, Kehinde Muibat and Banke, Idris Sherifat and Zakaria, Md Zuki Abu Bakar (2020) Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells. Cancer Nanotechnology, 11. art. no. 10. pp. 1-15. ISSN 1868-6958; ESSN: 1868-6966 https://cancer-nano.biomedcentral.com/articles/10.1186/s12645-020-00067-3#:~:text=Cockle%20shell%2Dderived%20aragonite%20calcium%20carbonate%20nanoparticles%20(CACNP)%20have,and%20is%20of%20low%20cost. 10.1186/s12645-020-00067-3 |
| spellingShingle | Ibiyeye, Kehinde Muibat Banke, Idris Sherifat Zakaria, Md Zuki Abu Bakar Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title | Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title_full | Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title_fullStr | Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title_full_unstemmed | Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title_short | Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| title_sort | cockle shell derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells |
| url | http://psasir.upm.edu.my/id/eprint/88180/1/ABSTRACT.pdf |
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