Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers
Introduction: Exposure of toluene can cause a decrease in glutathione concentration, increase in malondialdehyde and neurotoxic symptoms. The safe duration of toluene in hours/day for each person can vary. The purpose of this study is to determine the relationship between the safe duration of toluen...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Indian Journal of Forensic Medicine and Toxicology
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/88284/1/ABSTRACT.pdf |
| _version_ | 1796981952555778048 |
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| author | Ningrum, Diah Pramesthi Tualeka, Abdul Rohim Jalaludin, Juliana Russeng, Syamsiar S. Rahmawati, Pudji Ahsan, Ahsan Susilowati, Indah |
| author_facet | Ningrum, Diah Pramesthi Tualeka, Abdul Rohim Jalaludin, Juliana Russeng, Syamsiar S. Rahmawati, Pudji Ahsan, Ahsan Susilowati, Indah |
| author_sort | Ningrum, Diah Pramesthi |
| collection | UPM |
| description | Introduction: Exposure of toluene can cause a decrease in glutathione concentration, increase in malondialdehyde and neurotoxic symptoms. The safe duration of toluene in hours/day for each person can vary. The purpose of this study is to determine the relationship between the safe duration of toluene (hours/day) with the concentration of glutathione, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers. Methods: This research was observational with quantitative approach and cross-sectional design. The sampling technique used was accidental sampling with 25 respondents. The variables studied were safe
toluene duration (hours/day), glutathione concentration, malondialdehyde concentration, and neurotoxic symptoms. Data were analyzed using Pearson and Phi correlation. Result: The average of safe duration was 1,489 hours/day, glutathione concentration was 58,349 µg/L, and malondialdehyde was 7,847 MU. As many as 11 out of 14 workers experienced neurotoxic symptoms.
The relationship between safe duration (hours/day) with glutathione concentration (r=0.139) and malondialdehyde (r=-0.146) was very weak. While, the relationship between safe duration (hours/day) and
neurotoxic symptoms was weak (?=-0.223). Conclusion: The relationship between safe duration in hours/day with glutathione concentration and malondialdehyde was very weak, while relationship with neurotoxic symptoms was weak. |
| first_indexed | 2024-03-06T10:45:12Z |
| format | Article |
| id | upm.eprints-88284 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:45:12Z |
| publishDate | 2020 |
| publisher | Indian Journal of Forensic Medicine and Toxicology |
| record_format | dspace |
| spelling | upm.eprints-882842022-03-10T03:49:31Z http://psasir.upm.edu.my/id/eprint/88284/ Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers Ningrum, Diah Pramesthi Tualeka, Abdul Rohim Jalaludin, Juliana Russeng, Syamsiar S. Rahmawati, Pudji Ahsan, Ahsan Susilowati, Indah Introduction: Exposure of toluene can cause a decrease in glutathione concentration, increase in malondialdehyde and neurotoxic symptoms. The safe duration of toluene in hours/day for each person can vary. The purpose of this study is to determine the relationship between the safe duration of toluene (hours/day) with the concentration of glutathione, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers. Methods: This research was observational with quantitative approach and cross-sectional design. The sampling technique used was accidental sampling with 25 respondents. The variables studied were safe toluene duration (hours/day), glutathione concentration, malondialdehyde concentration, and neurotoxic symptoms. Data were analyzed using Pearson and Phi correlation. Result: The average of safe duration was 1,489 hours/day, glutathione concentration was 58,349 µg/L, and malondialdehyde was 7,847 MU. As many as 11 out of 14 workers experienced neurotoxic symptoms. The relationship between safe duration (hours/day) with glutathione concentration (r=0.139) and malondialdehyde (r=-0.146) was very weak. While, the relationship between safe duration (hours/day) and neurotoxic symptoms was weak (?=-0.223). Conclusion: The relationship between safe duration in hours/day with glutathione concentration and malondialdehyde was very weak, while relationship with neurotoxic symptoms was weak. Indian Journal of Forensic Medicine and Toxicology 2020 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/88284/1/ABSTRACT.pdf Ningrum, Diah Pramesthi and Tualeka, Abdul Rohim and Jalaludin, Juliana and Russeng, Syamsiar S. and Rahmawati, Pudji and Ahsan, Ahsan and Susilowati, Indah (2020) Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers. Indian Journal of Forensic Medicine and Toxicology, 14 (4). 868 - 874. ISSN 0973-9122; ESSN: 0973-9130 https://medicopublication.com/index.php/ijfmt/article/view/11602 10.37506/ijfmt.v14i4.11602 |
| spellingShingle | Ningrum, Diah Pramesthi Tualeka, Abdul Rohim Jalaludin, Juliana Russeng, Syamsiar S. Rahmawati, Pudji Ahsan, Ahsan Susilowati, Indah Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title | Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title_full | Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title_fullStr | Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title_full_unstemmed | Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title_short | Correlation of toluene safe duration (hours/day) and glutathione concentration, malondialdehyde and neurotoxic symptoms in Osowilangun shoe home industry workers |
| title_sort | correlation of toluene safe duration hours day and glutathione concentration malondialdehyde and neurotoxic symptoms in osowilangun shoe home industry workers |
| url | http://psasir.upm.edu.my/id/eprint/88284/1/ABSTRACT.pdf |
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