Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child?
A case of a toxigenic strain of Corynebacterium diphtheriae in an immunocompetent adult is presented, with the possibility of the adult acquiring the infection from her unvaccinated child. The abovementioned adult is a 29-year-old housewife who was previously immunised with diphtheria, tetanus, and...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2021
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/90400/1/2021062816112544_MJMHS_0915.pdf |
| _version_ | 1796982311453982720 |
|---|---|
| author | Kandasamy, Thenmalar Muhamad Damanhuri, Fatimahtuz Zahrah Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Ibrahim, Rosni |
| author_facet | Kandasamy, Thenmalar Muhamad Damanhuri, Fatimahtuz Zahrah Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Ibrahim, Rosni |
| author_sort | Kandasamy, Thenmalar |
| collection | UPM |
| description | A case of a toxigenic strain of Corynebacterium diphtheriae in an immunocompetent adult is presented, with the possibility of the adult acquiring the infection from her unvaccinated child. The abovementioned adult is a 29-year-old housewife who was previously immunised with diphtheria, tetanus, and pertussis (DTaP) vaccination in childhood, who presented fever, cough, sore throat, hoarseness of voice, odynophagia, and bilaterally enlarged tonsils. A throat swab confirmed the presence of toxigenic Corynebacterium diphtheriae. The patient was given 80,000 international units (IU) dose of diphtheria antitoxin (DAT) and treated with 2.4 million units (MU) QID intravenous penicillin and oral erythromycin 800 mg twice daily for two weeks. The patient responded well to the treatment and recovered with no cardiovascular or neurotoxicity. |
| first_indexed | 2024-03-06T10:50:10Z |
| format | Article |
| id | upm.eprints-90400 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T10:50:10Z |
| publishDate | 2021 |
| publisher | Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-904002021-09-10T01:43:17Z http://psasir.upm.edu.my/id/eprint/90400/ Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? Kandasamy, Thenmalar Muhamad Damanhuri, Fatimahtuz Zahrah Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Ibrahim, Rosni A case of a toxigenic strain of Corynebacterium diphtheriae in an immunocompetent adult is presented, with the possibility of the adult acquiring the infection from her unvaccinated child. The abovementioned adult is a 29-year-old housewife who was previously immunised with diphtheria, tetanus, and pertussis (DTaP) vaccination in childhood, who presented fever, cough, sore throat, hoarseness of voice, odynophagia, and bilaterally enlarged tonsils. A throat swab confirmed the presence of toxigenic Corynebacterium diphtheriae. The patient was given 80,000 international units (IU) dose of diphtheria antitoxin (DAT) and treated with 2.4 million units (MU) QID intravenous penicillin and oral erythromycin 800 mg twice daily for two weeks. The patient responded well to the treatment and recovered with no cardiovascular or neurotoxicity. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2021-07 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/90400/1/2021062816112544_MJMHS_0915.pdf Kandasamy, Thenmalar and Muhamad Damanhuri, Fatimahtuz Zahrah and Zaini, Adillahtul Bushro and Zakariah, Siti Zulaikha and Ibrahim, Rosni (2021) Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? Malaysian Journal of Medicine and Health Sciences, 17 (3). pp. 311-314. ISSN 1675-8544; ESSN: 2636-9346 https://medic.upm.edu.my/upload/dokumen/2021062816112544_MJMHS_0915.pdf |
| spellingShingle | Kandasamy, Thenmalar Muhamad Damanhuri, Fatimahtuz Zahrah Zaini, Adillahtul Bushro Zakariah, Siti Zulaikha Ibrahim, Rosni Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title | Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title_full | Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title_fullStr | Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title_full_unstemmed | Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title_short | Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? |
| title_sort | adult diphteria possible transmission of corynebacterium diphtheriae from unvaccinated child |
| url | http://psasir.upm.edu.my/id/eprint/90400/1/2021062816112544_MJMHS_0915.pdf |
| work_keys_str_mv | AT kandasamythenmalar adultdiphteriapossibletransmissionofcorynebacteriumdiphtheriaefromunvaccinatedchild AT muhamaddamanhurifatimahtuzzahrah adultdiphteriapossibletransmissionofcorynebacteriumdiphtheriaefromunvaccinatedchild AT zainiadillahtulbushro adultdiphteriapossibletransmissionofcorynebacteriumdiphtheriaefromunvaccinatedchild AT zakariahsitizulaikha adultdiphteriapossibletransmissionofcorynebacteriumdiphtheriaefromunvaccinatedchild AT ibrahimrosni adultdiphteriapossibletransmissionofcorynebacteriumdiphtheriaefromunvaccinatedchild |