LRG1 promotes metastatic dissemination of melanoma through regulating EGFR/STAT3 signalling

LRG1 promotes metastatic dissemination of melanoma through regulating EGFR/STAT3 signalling

Show other versions (1)

Although less common, melanoma is the deadliest form of skin cancer largely due to its highly metastatic nature. Currently, there are limited treatment options for metastatic melanoma and many of them could cause serious side effects. A better understanding of the molecular mechanisms underlying the...

Full description

Bibliographic Details
Main Authors:	Kwan, Yuet Ping, Teo, Melissa Hui Yen, Lim, Jonathan Chee Woei, Tan, Michelle Siying, Rosellinny, Graciella, Wahli, Walter, Wang, Xiaomeng
Format:	Article
Language:	English
Published:	Multidisciplinary Digital Publishing Institute 2021
Online Access:	http://psasir.upm.edu.my/id/eprint/94059/1/94059.pdf

Similar Items

LRG1 promotes metastatic dissemination of melanoma through regulating EGFR/STAT3 signalling
by: Kwan, Yuet Ping, et al.
Published: (2021)

The role of PPARβ/δ in melanoma metastasis
by: Lim, Jonathan Chee Woei, et al.
Published: (2018)

Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway
by: Athina Dritsoula, et al.
Published: (2022-03-01)

Metastatic heart lesion in disseminated melanoma
by: G. G. Hubulava, et al.
Published: (2024-10-01)

Publisher Correction: Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway
by: Athina Dritsoula, et al.
Published: (2022-03-01)

LRG-1 promotes pancreatic cancer growth and metastasis via modulation of the EGFR/p38 signaling
by: Zhi-Bo Xie, et al.
Published: (2019-02-01)

The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure
by: Song, Weihua, et al.
Published: (2015)

Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation
by: Jimin Yang, et al.
Published: (2023-05-01)

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression
by: Sng, Ming Keat, et al.
Published: (2018)

The Metastatic Capacity of Melanoma Reveals Alternative Pathways of Cancer Dissemination
by: Michela Corsini, et al.
Published: (2021-10-01)

Application of LRG mechanism in normal pressure hydrocephalus
by: Luyao Ma, et al.
Published: (2024-01-01)

Targeted degradation of LRG1 to attenuate renal fibrosis
by: Linyao Fan, et al.
Published: (2024-08-01)

The disruptive role of LRG1 on the vasculature and perivascular microenvironment
by: Athina Dritsoula, et al.
Published: (2024-04-01)

Understanding LrgAB Regulation of Streptococcus mutans Metabolism
by: Sang-Joon Ahn, et al.
Published: (2020-09-01)

Immunotherapy in Metastatic Mucosal Melanoma with Disseminated Intravascular Coagulation: A Case of Success
by: Helena Luna Pais, et al.
Published: (2021-01-01)

Effective Immunotherapy in Bone Marrow Metastatic Melanoma Presenting with Disseminated Intravascular Coagulopathy
by: Bolanle Gbadamosi, et al.
Published: (2018-01-01)

The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.
by: Quentin Raimbourg, et al.
Published: (2013-01-01)

LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
by: Chan Hee J Choi, et al.
Published: (2022-11-01)

Regulation of cid and lrg expression by CodY in Streptococcus mutans
by: Sang‐Joon Ahn, et al.
Published: (2020-07-01)

pSTAT3 transactivates EGFR in maintaining EGFR protein homeostasis and EGFR-TKI resistance
by: Ao Juan, et al.
Published: (2024-09-01)

The 2dF-SDSS LRG and QSO Survey: The spectroscopic QSO catalogue
by: Croom, S, et al.
Published: (2008)

Angular correlation function from sample covariance with BOSS and eBOSS LRG
by: Paula S. Ferreira, et al.
Published: (2024-05-01)

LRG1 Contributes to the Pathogenesis of Multiple Kidney Diseases: A Comprehensive Review
by: Chunyan Chen, et al.
Published: (2024-04-01)

Role of VEGF-A and LRG1 in Abnormal Angiogenesis Associated With Diabetic Nephropathy
by: Afei Zhang, et al.
Published: (2020-08-01)

Acetate and Potassium Modulate the Stationary-Phase Activation of lrgAB in Streptococcus mutans
by: Sang-Joon Ahn, et al.
Published: (2020-03-01)

Four cases of disseminated herpes simplex virus following talimogene laherparepvec injections for unresectable metastatic melanoma
by: Kate E. Beekman, BS, et al.
Published: (2023-03-01)

Cariogenic potential of the Streptococcus mutans Cid/Lrg system: an in vivo animal case study
by: Sang-Joon Ahn, et al.
Published: (2024-12-01)

Activated platelet-derived exosomal LRG1 promotes multiple myeloma cell growth
by: Meng Gao, et al.
Published: (2024-06-01)

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination.
by: Pinner, S, et al.
Published: (2009)

Elevation of a Novel Angiogenic Factor, Leucine-Rich- 2-Glycoprotein (LRG1), Is Associated With Arterial Stiffness, Endothelial Dysfunction, and Peripheral Arterial Disease in Patients With Type 2 Diabetes
by: Pek, Sharon L. T., et al.
Published: (2015)

Metastases in the breast from disseminating melanoma
by: A Oehlers-Wetzel, et al.
Published: (2010-03-01)

Metastatic melanoma of the gallbladder
by: Ninić Aleksandar, et al.
Published: (2024-01-01)

Metastatic melanoma and pregnancy
by: Nikolin Borislava L., et al.
Published: (2005-01-01)

The 2dF-SDSS LRG and QSO Survey: QSO clustering and the L-z degeneracy
by: Angela, J, et al.
Published: (2006)

The role of leucine-rich alpha-2-glycoprotein 1 (LRG1) in colorectal cancer cells
by: Chew, Clement Kai Hong
Published: (2016)

LRG1 predicts the prognosis and is associated with immune infiltration in thyroid cancer: a bioinformatics study
by: Zherui Fu, et al.
Published: (2023-12-01)

LRG1 Is Involved in the Progression of Ovarian Cancer via Modulating FAK/AKT Signaling Pathway
by: Dongling Wu, et al.
Published: (2023-05-01)

The mouse resistance protein Irgm1 (LRG-47): a regulator or an effector of pathogen defense?
by: Julia P Hunn, et al.
Published: (2010-01-01)

CidA and LrgA: a “Hole” Lot More than Programmed Cell Death
by: Maisem Laabei, et al.
Published: (2022-06-01)

LRG1 promotes corneal angiogenesis and lymphangiogenesis in a corneal alkali burn mouse model
by: Shan Song, et al.
Published: (2020-03-01)