Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis

Background: Rheumatoid arthritis is a chronic inflammatory and systemic autoimmune disease associated with synovial fluid inflammatory lesions and articular changes. The aim of the present study was to determine socioeconomic inequality in RA patients using a meta-analysis approach. Methods: A syste...

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Main Authors: Salari, Nader, Kazeminia, Mohsen, Shohaimi, Shamarina, Mohammadi, Masoud
Format: Article
Published: Springer UK 2021
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author Salari, Nader
Kazeminia, Mohsen
Shohaimi, Shamarina
Mohammadi, Masoud
author_facet Salari, Nader
Kazeminia, Mohsen
Shohaimi, Shamarina
Mohammadi, Masoud
author_sort Salari, Nader
collection UPM
description Background: Rheumatoid arthritis is a chronic inflammatory and systemic autoimmune disease associated with synovial fluid inflammatory lesions and articular changes. The aim of the present study was to determine socioeconomic inequality in RA patients using a meta-analysis approach. Methods: A systematic search of national and international databases of SID, MagIran, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) was conducted to find articles published from 1988 to March 2020. Random effects model was used for analysis and heterogeneity of studies was investigated using I2 index. Data analysis was then carried out using Comprehensive Meta-Analysis (Ver. 2). Results: A total of 51 articles with a total sample size of 48,195 individuals were included in the meta-analysis in all the components. The results showed that 18.9% (95% CI: 4.9–13.25%) of patients were single patients, 70.6% (95% CI: 63.5–76.8%) were married, 31.6% (95% CI: 24.5–39.7%) had low economic status, 52.1% (95% CI: 5.8–44.53%) had moderate economic status, level of education was below diploma in 33% (95% CI: 27.1–39.5%) of cases, 36.2% (95% CI: 27.3–46.1%) were smokers, and 8.8% (95% CI: 2.8–24.1%) of patients were unemployed. Conclusion: The results of the present study indicate high socioeconomic inequality in RA patients in the main components of the study. Hence, to improve the aforementioned status and find causes and do the monitoring at all levels, appropriate solutions must be adopted by providing feedback to policy-makers. Key Points: • The results showed that 18.9% (95% CI: 4.9–13.25%) of patients were single patients. • 70.6% (95% CI: 63.5–76.8%) were married and 31.6% (95% CI: 24.5–39.7%) had low economic status. • 52.1% (95% CI: 5.8–44.53%) had moderate economic status; 36.2% (95% CI: 27.3–46.1%) were smokers.
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spelling upm.eprints-950972023-06-19T08:26:05Z http://psasir.upm.edu.my/id/eprint/95097/ Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis Salari, Nader Kazeminia, Mohsen Shohaimi, Shamarina Mohammadi, Masoud Background: Rheumatoid arthritis is a chronic inflammatory and systemic autoimmune disease associated with synovial fluid inflammatory lesions and articular changes. The aim of the present study was to determine socioeconomic inequality in RA patients using a meta-analysis approach. Methods: A systematic search of national and international databases of SID, MagIran, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) was conducted to find articles published from 1988 to March 2020. Random effects model was used for analysis and heterogeneity of studies was investigated using I2 index. Data analysis was then carried out using Comprehensive Meta-Analysis (Ver. 2). Results: A total of 51 articles with a total sample size of 48,195 individuals were included in the meta-analysis in all the components. The results showed that 18.9% (95% CI: 4.9–13.25%) of patients were single patients, 70.6% (95% CI: 63.5–76.8%) were married, 31.6% (95% CI: 24.5–39.7%) had low economic status, 52.1% (95% CI: 5.8–44.53%) had moderate economic status, level of education was below diploma in 33% (95% CI: 27.1–39.5%) of cases, 36.2% (95% CI: 27.3–46.1%) were smokers, and 8.8% (95% CI: 2.8–24.1%) of patients were unemployed. Conclusion: The results of the present study indicate high socioeconomic inequality in RA patients in the main components of the study. Hence, to improve the aforementioned status and find causes and do the monitoring at all levels, appropriate solutions must be adopted by providing feedback to policy-makers. Key Points: • The results showed that 18.9% (95% CI: 4.9–13.25%) of patients were single patients. • 70.6% (95% CI: 63.5–76.8%) were married and 31.6% (95% CI: 24.5–39.7%) had low economic status. • 52.1% (95% CI: 5.8–44.53%) had moderate economic status; 36.2% (95% CI: 27.3–46.1%) were smokers. Springer UK 2021-06-22 Article PeerReviewed Salari, Nader and Kazeminia, Mohsen and Shohaimi, Shamarina and Mohammadi, Masoud (2021) Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis. Clinical Rheumatology, 40 (11). 4511 - 4525. ISSN 0770-3198; ESSN: 1434-9949 https://link.springer.com/article/10.1007/s10067-021-05829-x 10.1007/s10067-021-05829-x
spellingShingle Salari, Nader
Kazeminia, Mohsen
Shohaimi, Shamarina
Mohammadi, Masoud
Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title_full Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title_fullStr Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title_full_unstemmed Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title_short Socioeconomic inequality in patients with rheumatoid arthritis: a systematic review and meta-analysis
title_sort socioeconomic inequality in patients with rheumatoid arthritis a systematic review and meta analysis
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AT kazeminiamohsen socioeconomicinequalityinpatientswithrheumatoidarthritisasystematicreviewandmetaanalysis
AT shohaimishamarina socioeconomicinequalityinpatientswithrheumatoidarthritisasystematicreviewandmetaanalysis
AT mohammadimasoud socioeconomicinequalityinpatientswithrheumatoidarthritisasystematicreviewandmetaanalysis