TGF-β-induced fibrosis: a review on the underlying mechanism and potential therapeutic strategies

TGF-β-induced fibrosis: a review on the underlying mechanism and potential therapeutic strategies

Transforming growth factor-beta (TGF-β) plays multiple homeostatic roles in the regulation of inflammation, proliferation, differentiation and would healing of various tissues. Many studies have demonstrated that TGF-β stimulates activation and proliferation of fibroblasts, which result in extracell...

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Bibliographic Details
Main Authors:	Ong, Chun Hao, Tham, Chau Ling, Harith, Hanis Hazeera, Firdaus, Nazmi, Israf, Daud Ahmad
Format:	Article
Published:	Elsevier 2021

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