The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils
Antibiotic resistance is a major global health issue that has seen alarming rates of increase in all parts of the world over the past two decades. The surge in antibiotic resistance has resulted in longer hospital stays, higher medical costs, and elevated mortality rates. Constant attempts have been...
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Sage Publications
2021
|
| Acesso em linha: | http://psasir.upm.edu.my/id/eprint/95531/1/The%20missing%20piece%3B%20recent%20approaches%20investigating%20the%20antimicrobial%20mode%20of%20action%20of%20essential%20oils.pdf |
| _version_ | 1825937591273259008 |
|---|---|
| author | Yang, Shun Kai Tan, Ngai Paing Chong, Chun Wie Abushelaibi, Aisha Lim, Swee Hua Erin Lai, Kok Song |
| author_facet | Yang, Shun Kai Tan, Ngai Paing Chong, Chun Wie Abushelaibi, Aisha Lim, Swee Hua Erin Lai, Kok Song |
| author_sort | Yang, Shun Kai |
| collection | UPM |
| description | Antibiotic resistance is a major global health issue that has seen alarming rates of increase in all parts of the world over the past two decades. The surge in antibiotic resistance has resulted in longer hospital stays, higher medical costs, and elevated mortality rates. Constant attempts have been made to discover newer and more effective antimicrobials to reduce the severity of antibiotic resistance. Plant secondary metabolites, such as essential oils, have been the major focus due to their complexity and bioactive nature. However, the underlying mechanism of their antimicrobial effect remains largely unknown. Understanding the antimicrobial mode of action of essential oils is crucial in developing potential strategies for the use of essential oils in a clinical setting. Recent advances in genomics and proteomics have enhanced our understanding of the antimicrobial mode of action of essential oils. We might well be at the dawn of completing a mystery on how essential oils carry out their antimicrobial activities. Therefore, an overview of essential oils with regard to their antimicrobial activities and mode of action is discussed in this review. Recent approaches used in identifying the antimicrobial mode of action of essential oils, specifically from the perspective of genomics and proteomics, are also synthesized. Based on the information gathered from this review, we offer recommendations for future strategies and prospects for the study of essential oils and their function as antimicrobials. |
| first_indexed | 2024-03-06T11:01:50Z |
| format | Article |
| id | upm.eprints-95531 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T11:01:50Z |
| publishDate | 2021 |
| publisher | Sage Publications |
| record_format | dspace |
| spelling | upm.eprints-955312022-08-22T03:22:55Z http://psasir.upm.edu.my/id/eprint/95531/ The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils Yang, Shun Kai Tan, Ngai Paing Chong, Chun Wie Abushelaibi, Aisha Lim, Swee Hua Erin Lai, Kok Song Antibiotic resistance is a major global health issue that has seen alarming rates of increase in all parts of the world over the past two decades. The surge in antibiotic resistance has resulted in longer hospital stays, higher medical costs, and elevated mortality rates. Constant attempts have been made to discover newer and more effective antimicrobials to reduce the severity of antibiotic resistance. Plant secondary metabolites, such as essential oils, have been the major focus due to their complexity and bioactive nature. However, the underlying mechanism of their antimicrobial effect remains largely unknown. Understanding the antimicrobial mode of action of essential oils is crucial in developing potential strategies for the use of essential oils in a clinical setting. Recent advances in genomics and proteomics have enhanced our understanding of the antimicrobial mode of action of essential oils. We might well be at the dawn of completing a mystery on how essential oils carry out their antimicrobial activities. Therefore, an overview of essential oils with regard to their antimicrobial activities and mode of action is discussed in this review. Recent approaches used in identifying the antimicrobial mode of action of essential oils, specifically from the perspective of genomics and proteomics, are also synthesized. Based on the information gathered from this review, we offer recommendations for future strategies and prospects for the study of essential oils and their function as antimicrobials. Sage Publications 2021 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/95531/1/The%20missing%20piece%3B%20recent%20approaches%20investigating%20the%20antimicrobial%20mode%20of%20action%20of%20essential%20oils.pdf Yang, Shun Kai and Tan, Ngai Paing and Chong, Chun Wie and Abushelaibi, Aisha and Lim, Swee Hua Erin and Lai, Kok Song (2021) The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils. Evolutionary Bioinformatics, 17. pp. 1-6. ISSN 1176-9343 https://journals.sagepub.com/doi/10.1177/1176934320938391 10.1177/1176934320938391 |
| spellingShingle | Yang, Shun Kai Tan, Ngai Paing Chong, Chun Wie Abushelaibi, Aisha Lim, Swee Hua Erin Lai, Kok Song The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title | The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title_full | The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title_fullStr | The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title_full_unstemmed | The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title_short | The missing piece: recent approaches investigating the antimicrobial mode of action of essential oils |
| title_sort | missing piece recent approaches investigating the antimicrobial mode of action of essential oils |
| url | http://psasir.upm.edu.my/id/eprint/95531/1/The%20missing%20piece%3B%20recent%20approaches%20investigating%20the%20antimicrobial%20mode%20of%20action%20of%20essential%20oils.pdf |
| work_keys_str_mv | AT yangshunkai themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT tanngaipaing themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT chongchunwie themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT abushelaibiaisha themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT limsweehuaerin themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT laikoksong themissingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT yangshunkai missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT tanngaipaing missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT chongchunwie missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT abushelaibiaisha missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT limsweehuaerin missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils AT laikoksong missingpiecerecentapproachesinvestigatingtheantimicrobialmodeofactionofessentialoils |