A review on therapeutic effects of Labisia pumila on female reproductive diseases

The Labisia pumila (LP) is a traditional plant that is locally known as Kacip Fatimah, Selusuh Fatimah, or Pokok Ringgang by the Malaysian indigenous people. It is believed to facilitate their childbirth, treating their postchild birth and menstrual irregularities. The water extract of LP has shown...

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Main Authors: Zakaria, Alif Aiman, Mohd Noor, Mohd Hezmee, Ahmad, Hafandi, Abu Hassim, Hasliza, Mazlan, Mazlina, Ab Latip, Mohd Qayyum
Format: Article
Published: Hindawi 2021
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author Zakaria, Alif Aiman
Mohd Noor, Mohd Hezmee
Ahmad, Hafandi
Abu Hassim, Hasliza
Mazlan, Mazlina
Ab Latip, Mohd Qayyum
author_facet Zakaria, Alif Aiman
Mohd Noor, Mohd Hezmee
Ahmad, Hafandi
Abu Hassim, Hasliza
Mazlan, Mazlina
Ab Latip, Mohd Qayyum
author_sort Zakaria, Alif Aiman
collection UPM
description The Labisia pumila (LP) is a traditional plant that is locally known as Kacip Fatimah, Selusuh Fatimah, or Pokok Ringgang by the Malaysian indigenous people. It is believed to facilitate their childbirth, treating their postchild birth and menstrual irregularities. The water extract of LP has shown to contain bioactive compounds such as flavonoids, ascorbic acid, β-carotene, anthocyanin, and phenolic acid, which contribute extensive antioxidant, anti-inflammatory, antimicrobial, and antifungal. The LP ethanolic extract exhibits significant estrogenic effects on human endomentrial adenocarcinoma cell in estrogen-free basal medium and promoting an increase in secretion of alkaline phosphate. Water based has been used for many generations, and studies had reported that it could displace in binding the antibodies and increase the estradiol production making it similar to esterone and estradiol hormone. LP extract poses a potential and beneficial aspect in medical and cosmeceutical applications. This is mainly due to its phytoestrogen properties of the LP. However, there is a specific functionality in the application of LP extract, due to specific functional group in phytoconstituent of LP. Apart from that, the extraction solvent is important in preparing the LP extract as it poses some significant and mild side effects towards consuming the LP extracts. The current situation of women reproductive disease such as postmenopausal syndrome and polycystic ovary syndrome is increasing. Thus, it is important to find ways in alternative treatment for women reproductive disease that is less costly and low side effects. In conclusion, these studies proven that LP has the potential to be an alternative way in treating female reproductive related diseases such as in postmenopausal and polysystic ovarian syndrome women.
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spelling upm.eprints-960412023-03-09T01:31:06Z http://psasir.upm.edu.my/id/eprint/96041/ A review on therapeutic effects of Labisia pumila on female reproductive diseases Zakaria, Alif Aiman Mohd Noor, Mohd Hezmee Ahmad, Hafandi Abu Hassim, Hasliza Mazlan, Mazlina Ab Latip, Mohd Qayyum The Labisia pumila (LP) is a traditional plant that is locally known as Kacip Fatimah, Selusuh Fatimah, or Pokok Ringgang by the Malaysian indigenous people. It is believed to facilitate their childbirth, treating their postchild birth and menstrual irregularities. The water extract of LP has shown to contain bioactive compounds such as flavonoids, ascorbic acid, β-carotene, anthocyanin, and phenolic acid, which contribute extensive antioxidant, anti-inflammatory, antimicrobial, and antifungal. The LP ethanolic extract exhibits significant estrogenic effects on human endomentrial adenocarcinoma cell in estrogen-free basal medium and promoting an increase in secretion of alkaline phosphate. Water based has been used for many generations, and studies had reported that it could displace in binding the antibodies and increase the estradiol production making it similar to esterone and estradiol hormone. LP extract poses a potential and beneficial aspect in medical and cosmeceutical applications. This is mainly due to its phytoestrogen properties of the LP. However, there is a specific functionality in the application of LP extract, due to specific functional group in phytoconstituent of LP. Apart from that, the extraction solvent is important in preparing the LP extract as it poses some significant and mild side effects towards consuming the LP extracts. The current situation of women reproductive disease such as postmenopausal syndrome and polycystic ovary syndrome is increasing. Thus, it is important to find ways in alternative treatment for women reproductive disease that is less costly and low side effects. In conclusion, these studies proven that LP has the potential to be an alternative way in treating female reproductive related diseases such as in postmenopausal and polysystic ovarian syndrome women. Hindawi 2021 Article PeerReviewed Zakaria, Alif Aiman and Mohd Noor, Mohd Hezmee and Ahmad, Hafandi and Abu Hassim, Hasliza and Mazlan, Mazlina and Ab Latip, Mohd Qayyum (2021) A review on therapeutic effects of Labisia pumila on female reproductive diseases. Biomed Research International, 2021. pp. 1-9. ISSN 2314-6133: ESSN: 2314-6141 https://www.hindawi.com/journals/bmri/2021/9928199/ 10.1155/2021/9928199
spellingShingle Zakaria, Alif Aiman
Mohd Noor, Mohd Hezmee
Ahmad, Hafandi
Abu Hassim, Hasliza
Mazlan, Mazlina
Ab Latip, Mohd Qayyum
A review on therapeutic effects of Labisia pumila on female reproductive diseases
title A review on therapeutic effects of Labisia pumila on female reproductive diseases
title_full A review on therapeutic effects of Labisia pumila on female reproductive diseases
title_fullStr A review on therapeutic effects of Labisia pumila on female reproductive diseases
title_full_unstemmed A review on therapeutic effects of Labisia pumila on female reproductive diseases
title_short A review on therapeutic effects of Labisia pumila on female reproductive diseases
title_sort review on therapeutic effects of labisia pumila on female reproductive diseases
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