Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis

Background: Fungal infections including Candida albicans is one of the most important health concerns among type 2 diabetic patients. Therefore, this study aimed to determine the prevalence of C. albicans skin infection in patients with type 2 diabetes in a systematic review and meta-analysis. Metho...

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Main Authors: Rasoulpoor, Shna, Shohaimi, Shamarina, Salari, Nader, Raygani, Aliakbar Vaisi, Rasoulpoor, Shabnam, Shabani, Shervin, Jalali, Rostam, Mohammadi, Masoud
Format: Article
Published: Elsevier 2021
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author Rasoulpoor, Shna
Shohaimi, Shamarina
Salari, Nader
Raygani, Aliakbar Vaisi
Rasoulpoor, Shabnam
Shabani, Shervin
Jalali, Rostam
Mohammadi, Masoud
author_facet Rasoulpoor, Shna
Shohaimi, Shamarina
Salari, Nader
Raygani, Aliakbar Vaisi
Rasoulpoor, Shabnam
Shabani, Shervin
Jalali, Rostam
Mohammadi, Masoud
author_sort Rasoulpoor, Shna
collection UPM
description Background: Fungal infections including Candida albicans is one of the most important health concerns among type 2 diabetic patients. Therefore, this study aimed to determine the prevalence of C. albicans skin infection in patients with type 2 diabetes in a systematic review and meta-analysis. Methods: In this review study, data were extracted from national and international databases of SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) with no time limit until January 2021. The random effects model was used for doing analysis and the I2 index was used for assessing the heterogeneity of studies. Data were analyzed using Comprehensive Meta-Analysis (Version 2). Results: The prevalence of C. albicans skin infection in patients with type 2 diabetes was 11.4% (95% CI: 8.9%-14.4%) in 13 reviewed articles with a sample size of 1348. Regarding the heterogeneity based on meta-regression, there was a significant difference between the effect of sample size (P < 0.05) and the prevalence of C. albicans skin infection in patients with type 2 diabetes. Conclusion: The results of this study showed that C. albicans skin infection was high in type 2 diabetic patients in Iran. Therefore, to improve the aforementioned situation and to troubleshoot and monitor at all levels, appropriate policies should be adopted.
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spelling upm.eprints-962752023-01-31T02:56:10Z http://psasir.upm.edu.my/id/eprint/96275/ Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis Rasoulpoor, Shna Shohaimi, Shamarina Salari, Nader Raygani, Aliakbar Vaisi Rasoulpoor, Shabnam Shabani, Shervin Jalali, Rostam Mohammadi, Masoud Background: Fungal infections including Candida albicans is one of the most important health concerns among type 2 diabetic patients. Therefore, this study aimed to determine the prevalence of C. albicans skin infection in patients with type 2 diabetes in a systematic review and meta-analysis. Methods: In this review study, data were extracted from national and international databases of SID, MagIran, IranMedex, IranDoc, Google Scholar, Cochrane, Embase, ScienceDirect, Scopus, PubMed, and Web of Science (WoS) with no time limit until January 2021. The random effects model was used for doing analysis and the I2 index was used for assessing the heterogeneity of studies. Data were analyzed using Comprehensive Meta-Analysis (Version 2). Results: The prevalence of C. albicans skin infection in patients with type 2 diabetes was 11.4% (95% CI: 8.9%-14.4%) in 13 reviewed articles with a sample size of 1348. Regarding the heterogeneity based on meta-regression, there was a significant difference between the effect of sample size (P < 0.05) and the prevalence of C. albicans skin infection in patients with type 2 diabetes. Conclusion: The results of this study showed that C. albicans skin infection was high in type 2 diabetic patients in Iran. Therefore, to improve the aforementioned situation and to troubleshoot and monitor at all levels, appropriate policies should be adopted. Elsevier 2021 Article PeerReviewed Rasoulpoor, Shna and Shohaimi, Shamarina and Salari, Nader and Raygani, Aliakbar Vaisi and Rasoulpoor, Shabnam and Shabani, Shervin and Jalali, Rostam and Mohammadi, Masoud (2021) Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis. Journal of Diabetes and Metabolic Disorders, 20. 665 - 672. ISSN 2251-6581 https://link.springer.com/article/10.1007/s40200-021-00797-0 10.1007/s40200-021-00797-0
spellingShingle Rasoulpoor, Shna
Shohaimi, Shamarina
Salari, Nader
Raygani, Aliakbar Vaisi
Rasoulpoor, Shabnam
Shabani, Shervin
Jalali, Rostam
Mohammadi, Masoud
Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title_full Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title_fullStr Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title_full_unstemmed Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title_short Candida albicans skin infection in patients with type 2 diabetes: a systematic review and meta-analysis
title_sort candida albicans skin infection in patients with type 2 diabetes a systematic review and meta analysis
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