Central composite design for formulation and optimization of solid lipid nanoparticles to enhance oral bioavailability of Acyclovir
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute kidney injury. For this reason, a suitable deliv...
| Principais autores: | , , , , , |
|---|---|
| Formato: | Artigo |
| Publicado em: |
Multidisciplinary Digital Publishing Institute
2021
|