Diarylpentanoid (1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one) (MS13) exhibits anti-proliferative, apoptosis induction and anti-migration properties on androgen-independent human prostate cancer by targeting cell cycle-apoptosis and PI3K signalling pathways
Diarylpentanoids exhibit a high degree of anti-cancer activity and stability in vitro over curcumin in prostate cancer cells. Hence, this study aims to investigate the effects of a diarylpentanoid, 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one (MS13) on cytotoxicity, anti-proliferative, ap...
Main Authors: | Abd Wahab, Nurul Azwa, Abas, Faridah, Othman, Iekhsan, Naidu, Rakesh |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media
2021
|
Online Access: | http://psasir.upm.edu.my/id/eprint/96718/1/ABSTRACT.pdf |
Similar Items
-
Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one
by: Citalingam, Kamini, et al.
Published: (2015) -
Molecular mechanisms of antiproliferative and apoptosis activity by 1,5-bis(4-hydroxy-3 methoxyphenyl) 1,4-pentadiene-3-one (ms13) on human non-small cell lung cancer cells
by: Wan Mohd Tajuddin, Wan Nur Baitty, et al.
Published: (2021) -
Molecular Mechanisms of Antiproliferative and Apoptosis Activity by 1,5-Bis(4-Hydroxy-3-Methoxyphenyl)1,4-Pentadiene-3-one (MS13) on Human Non-Small Cell Lung Cancer Cells
by: Wan Nur Baitty Wan Mohd Tajuddin, et al.
Published: (2021-07-01) -
The Curcumin Analogue, MS13 (1,5-Bis(4-hydroxy-3- methoxyphenyl)-1,4-pentadiene-3-one), Inhibits Cell Proliferation and Induces Apoptosis in Primary and Metastatic Human Colon Cancer Cells
by: Nor Isnida Ismail, et al.
Published: (2020-08-01) -
Anti-Cancer Mechanisms of Diarylpentanoid MS17 (1,5-Bis(2-hydroxyphenyl)-1,4-pentadiene-3-one) in Human Colon Cancer Cells: A Proteomics Approach
by: Kha Wai Hon, et al.
Published: (2024-03-01)