Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis

Background: The benefits of qigong for systolic and diastolic blood pressure (BP) reduction have been noted in previously published systematic reviews; however, the data on its effectiveness has been at best scarce. We aimed to update the evidence of qigong on blood pressure reduction after taking i...

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Main Authors: Siew, Mooi Ching, Mokshashri, Naidu Ragubathi, Kannan, Maharajan Mari, Lee, Kai Wei, Sallahuddin, Nurin Amalina, Jun, Xun Ng, Wong, Jie Lin, Devaraj, Navin Kumar, Fan, Kee Hoo, Yee, Shen Loo, Veettil, Sajesh K.
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:http://psasir.upm.edu.my/id/eprint/97005/1/ABSTRACT.pdf
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author Siew, Mooi Ching
Mokshashri, Naidu Ragubathi
Kannan, Maharajan Mari
Lee, Kai Wei
Sallahuddin, Nurin Amalina
Jun, Xun Ng
Wong, Jie Lin
Devaraj, Navin Kumar
Fan, Kee Hoo
Yee, Shen Loo
Veettil, Sajesh K.
author_facet Siew, Mooi Ching
Mokshashri, Naidu Ragubathi
Kannan, Maharajan Mari
Lee, Kai Wei
Sallahuddin, Nurin Amalina
Jun, Xun Ng
Wong, Jie Lin
Devaraj, Navin Kumar
Fan, Kee Hoo
Yee, Shen Loo
Veettil, Sajesh K.
author_sort Siew, Mooi Ching
collection UPM
description Background: The benefits of qigong for systolic and diastolic blood pressure (BP) reduction have been noted in previously published systematic reviews; however, the data on its effectiveness has been at best scarce. We aimed to update the evidence of qigong on blood pressure reduction after taking into consideration the risks of random error and reliability of data in the cumulative meta-analysis using trial sequential analysis (TSA). Methods: Included trials were assessed using Cochrane risk of bias instrument. We performed meta-analysis with random-effects model and random errors were evaluated with TSA. We performed the search for the eligible randomized controlled trial (RCT) through Medline, Cinahl, Cochrane Central Register of Controlled Trials and also PubMed. Results: A total of 370 subjects sourced from seven eligible RCTs were entered into the analysis. The pooled results demonstrated the significant reduction with the use of qigong of the systolic blood pressure [weighted mean difference (WMD), − 10.66 mmHg (95% confidence interval (CI) = − 17.69,-3.62, p < 0.001] and diastolic BP [WMD, − 6.76 mmHg, 95% CI = − 12.22, − 1.30, p < 0.001] as compared to the control group. Conclusions: Significant reductions in BP is seen with the use of qigong as compared with the control group, suggesting that qigong may be used as a complementary therapy in the somewhat complicated management of hypertension.
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spelling upm.eprints-970052022-10-18T04:51:13Z http://psasir.upm.edu.my/id/eprint/97005/ Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis Siew, Mooi Ching Mokshashri, Naidu Ragubathi Kannan, Maharajan Mari Lee, Kai Wei Sallahuddin, Nurin Amalina Jun, Xun Ng Wong, Jie Lin Devaraj, Navin Kumar Fan, Kee Hoo Yee, Shen Loo Veettil, Sajesh K. Background: The benefits of qigong for systolic and diastolic blood pressure (BP) reduction have been noted in previously published systematic reviews; however, the data on its effectiveness has been at best scarce. We aimed to update the evidence of qigong on blood pressure reduction after taking into consideration the risks of random error and reliability of data in the cumulative meta-analysis using trial sequential analysis (TSA). Methods: Included trials were assessed using Cochrane risk of bias instrument. We performed meta-analysis with random-effects model and random errors were evaluated with TSA. We performed the search for the eligible randomized controlled trial (RCT) through Medline, Cinahl, Cochrane Central Register of Controlled Trials and also PubMed. Results: A total of 370 subjects sourced from seven eligible RCTs were entered into the analysis. The pooled results demonstrated the significant reduction with the use of qigong of the systolic blood pressure [weighted mean difference (WMD), − 10.66 mmHg (95% confidence interval (CI) = − 17.69,-3.62, p < 0.001] and diastolic BP [WMD, − 6.76 mmHg, 95% CI = − 12.22, − 1.30, p < 0.001] as compared to the control group. Conclusions: Significant reductions in BP is seen with the use of qigong as compared with the control group, suggesting that qigong may be used as a complementary therapy in the somewhat complicated management of hypertension. BioMed Central 2021 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/97005/1/ABSTRACT.pdf Siew, Mooi Ching and Mokshashri, Naidu Ragubathi and Kannan, Maharajan Mari and Lee, Kai Wei and Sallahuddin, Nurin Amalina and Jun, Xun Ng and Wong, Jie Lin and Devaraj, Navin Kumar and Fan, Kee Hoo and Yee, Shen Loo and Veettil, Sajesh K. (2021) Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis. BMC Complementary and Alternative Medicine, 21. art. no. 8. pp. 1-11. ISSN 1472-6882 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7789757/ 10.1186/s12906-020-03172-3
spellingShingle Siew, Mooi Ching
Mokshashri, Naidu Ragubathi
Kannan, Maharajan Mari
Lee, Kai Wei
Sallahuddin, Nurin Amalina
Jun, Xun Ng
Wong, Jie Lin
Devaraj, Navin Kumar
Fan, Kee Hoo
Yee, Shen Loo
Veettil, Sajesh K.
Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title_full Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title_fullStr Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title_full_unstemmed Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title_short Effects of qigong on systolic and diastolic blood pressure lowering: a systematic review with meta-analysis and trial sequential analysis
title_sort effects of qigong on systolic and diastolic blood pressure lowering a systematic review with meta analysis and trial sequential analysis
url http://psasir.upm.edu.my/id/eprint/97005/1/ABSTRACT.pdf
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