Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia
Caprine arthritis-encephalitis virus (CAEV) is a member of the genus lentivirus causing caprine arthritis-encephalitis (CAE), a chronic inflammatory condition affecting the lungs, joints, udder and central nervous system of small ruminants such as sheep and goats. CAE is distributed worldwide and i...
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Format: | Article |
Language: | English |
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Universiti Sains Malaysia
2021
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Online Access: | http://psasir.upm.edu.my/id/eprint/97411/1/ABSTRACT.pdf |
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author | Bura, Thlama Paul Hashi, Hamza Abdirahman Burhannuddin, Nurul Najwa Lim, Eric Teik Chung Abdullah Jesse, Faez Firdaus Mohd Lila, Mohd Azmi Haron, Abd Wahid Che Amat, Azlan Abba, Yusuf Maqbool, Arsalan Ur Rehman Bhutto, Khaleeq Mat Isa, Kamarulrizal Amira, Nur Azhar Odhah, Mohammed Naji Hambali, Idris Umar Norsidin, Mohd Jefri |
author_facet | Bura, Thlama Paul Hashi, Hamza Abdirahman Burhannuddin, Nurul Najwa Lim, Eric Teik Chung Abdullah Jesse, Faez Firdaus Mohd Lila, Mohd Azmi Haron, Abd Wahid Che Amat, Azlan Abba, Yusuf Maqbool, Arsalan Ur Rehman Bhutto, Khaleeq Mat Isa, Kamarulrizal Amira, Nur Azhar Odhah, Mohammed Naji Hambali, Idris Umar Norsidin, Mohd Jefri |
author_sort | Bura, Thlama Paul |
collection | UPM |
description | Caprine arthritis-encephalitis virus (CAEV) is a member of the genus lentivirus causing caprine arthritis-encephalitis (CAE), a chronic inflammatory condition affecting the lungs, joints, udder and central nervous system of small ruminants such as sheep and goats.
CAE is distributed worldwide and is recognised as a significant cause of morbidity and decreased milk production in dairy goats. Earlier studies highlighted the clinicopathological features and supplied preliminary serological evidence for the existence of CAE among selected goat herds in Malaysia. Therefore, this study aims to provide further insights into the seroprevalence and contributing factors of CAE among sheep and goat herds in two states of Peninsular Malaysia. The blood samples and biodata were randomly collected from a total of 262 individual sheep (40) and goat (222) in seven smallholder farms. Blood sera were tested for specific anti-CAEV antibodies using Qayee-Bio CAEV sandwich-ELISA
test kits according to standard procedures. Our results of the study revealed 21.4% (95% CI: 15.8–28.6) apparent and 20.6% (95% CI: 14.5–27.8) true seroprevalence with significant differences (p < 0.05) in seroconversion rates between the states, farms, production systems
and breeds of small ruminants. The prevalence of CAE in the Malaysian Peninsular is a potential threat to the small ruminant industry and developing agricultural economy. Further studies are required to determine the genetic characteristics, distribution and risk factors of CAEV for effective prevention and control in Malaysia. |
first_indexed | 2024-03-06T11:05:53Z |
format | Article |
id | upm.eprints-97411 |
institution | Universiti Putra Malaysia |
language | English |
last_indexed | 2024-03-06T11:05:53Z |
publishDate | 2021 |
publisher | Universiti Sains Malaysia |
record_format | dspace |
spelling | upm.eprints-974112022-08-26T08:36:14Z http://psasir.upm.edu.my/id/eprint/97411/ Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia Bura, Thlama Paul Hashi, Hamza Abdirahman Burhannuddin, Nurul Najwa Lim, Eric Teik Chung Abdullah Jesse, Faez Firdaus Mohd Lila, Mohd Azmi Haron, Abd Wahid Che Amat, Azlan Abba, Yusuf Maqbool, Arsalan Ur Rehman Bhutto, Khaleeq Mat Isa, Kamarulrizal Amira, Nur Azhar Odhah, Mohammed Naji Hambali, Idris Umar Norsidin, Mohd Jefri Caprine arthritis-encephalitis virus (CAEV) is a member of the genus lentivirus causing caprine arthritis-encephalitis (CAE), a chronic inflammatory condition affecting the lungs, joints, udder and central nervous system of small ruminants such as sheep and goats. CAE is distributed worldwide and is recognised as a significant cause of morbidity and decreased milk production in dairy goats. Earlier studies highlighted the clinicopathological features and supplied preliminary serological evidence for the existence of CAE among selected goat herds in Malaysia. Therefore, this study aims to provide further insights into the seroprevalence and contributing factors of CAE among sheep and goat herds in two states of Peninsular Malaysia. The blood samples and biodata were randomly collected from a total of 262 individual sheep (40) and goat (222) in seven smallholder farms. Blood sera were tested for specific anti-CAEV antibodies using Qayee-Bio CAEV sandwich-ELISA test kits according to standard procedures. Our results of the study revealed 21.4% (95% CI: 15.8–28.6) apparent and 20.6% (95% CI: 14.5–27.8) true seroprevalence with significant differences (p < 0.05) in seroconversion rates between the states, farms, production systems and breeds of small ruminants. The prevalence of CAE in the Malaysian Peninsular is a potential threat to the small ruminant industry and developing agricultural economy. Further studies are required to determine the genetic characteristics, distribution and risk factors of CAEV for effective prevention and control in Malaysia. Universiti Sains Malaysia 2021 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/97411/1/ABSTRACT.pdf Bura, Thlama Paul and Hashi, Hamza Abdirahman and Burhannuddin, Nurul Najwa and Lim, Eric Teik Chung and Abdullah Jesse, Faez Firdaus and Mohd Lila, Mohd Azmi and Haron, Abd Wahid and Che Amat, Azlan and Abba, Yusuf and Maqbool, Arsalan and Ur Rehman Bhutto, Khaleeq and Mat Isa, Kamarulrizal and Amira, Nur Azhar and Odhah, Mohammed Naji and Hambali, Idris Umar and Norsidin, Mohd Jefri (2021) Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia. Tropical Life Sciences Research, 32 (2). 83 - 96. ISSN 1985-3718; ESSN: 2180-4249 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8300945/ 10.21315/tlsr2021.32.2.6 |
spellingShingle | Bura, Thlama Paul Hashi, Hamza Abdirahman Burhannuddin, Nurul Najwa Lim, Eric Teik Chung Abdullah Jesse, Faez Firdaus Mohd Lila, Mohd Azmi Haron, Abd Wahid Che Amat, Azlan Abba, Yusuf Maqbool, Arsalan Ur Rehman Bhutto, Khaleeq Mat Isa, Kamarulrizal Amira, Nur Azhar Odhah, Mohammed Naji Hambali, Idris Umar Norsidin, Mohd Jefri Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title | Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title_full | Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title_fullStr | Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title_full_unstemmed | Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title_short | Further insights into Caprine Arthritis Encephalitis (CAE): the current status of seroprevalence among small ruminants in two selected states of Peninsular Malaysia |
title_sort | further insights into caprine arthritis encephalitis cae the current status of seroprevalence among small ruminants in two selected states of peninsular malaysia |
url | http://psasir.upm.edu.my/id/eprint/97411/1/ABSTRACT.pdf |
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