YB-1 And CTCF Differentially Regulate The 5-HTT Polymorphic Intron 2 Enhancer Which Predisposes To A Variety Of Neurological Disorders.

YB-1 And CTCF Differentially Regulate The 5-HTT Polymorphic Intron 2 Enhancer Which Predisposes To A Variety Of Neurological Disorders.

Mutation or inappropriate expression of the serotonin transporter (5-HTT) gene has been postulated as a possible predisposing factor in many CNS-related disorders, including numerous studies of affective disorders. The human gene encompasses 15 exons spanning -31 kb on chromosome 17qll (Lesch et aI....

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Bibliographic Details
Main Authors: Klenova, Elena, C. Scott,, Alison, Roberts, Julian, Shamsuddin, Shaharum, A. Lovejoy, Elizabeth, Bergmann, Stephan, J. Bubb, Vivien, Dieter Royer, Hans, P. Quinn, John
Format: Article
Language:English
Published: 2004
Subjects:
R735-854 Medical education. Medical schools. Research
Online Access:http://eprints.usm.my/10906/1/YB-1_and_CTCF_Differentially_Regulate_the_5-HTT_Polymorphic_%28PPSains_Kesihatan%29.pdf
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Summary:Mutation or inappropriate expression of the serotonin transporter (5-HTT) gene has been postulated as a possible predisposing factor in many CNS-related disorders, including numerous studies of affective disorders. The human gene encompasses 15 exons spanning -31 kb on chromosome 17qll (Lesch et aI., 1994).

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