Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice.
Pleurotus sajor-caju (oyster mushroom, PSC) is widely used in culinary due to its various benefits on human health. However, no study has been reported on its immunomodulating properties. Cultivated mushroom powder was used for hot aqueous extraction using Soxhlet technique. The PSC extract was susp...
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| Format: | Article |
| Language: | English |
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Research & Reviews
2014
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| Online Access: | http://eprints.usm.my/27595/1/AA_Nurul_MUHA.pdf |
| _version_ | 1825831882474913792 |
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| author | Nurul, A. A. Jonathan, M. A. Jamaruddin, M. A. Wan Rosli, W. I. |
| author_facet | Nurul, A. A. Jonathan, M. A. Jamaruddin, M. A. Wan Rosli, W. I. |
| author_sort | Nurul, A. A. |
| collection | USM |
| description | Pleurotus sajor-caju (oyster mushroom, PSC) is widely used in culinary due to its various benefits on human health. However, no study has been reported on its immunomodulating properties. Cultivated mushroom powder was used for hot aqueous extraction using Soxhlet technique. The PSC extract was suspended into CMC and prepared into 3 groups: 0.2 g/kg, 1g/kg and 2g/kg. Balb/c mice were orally fed daily for 21 consecutive days. Treatment of mice with various concentrations of PSC showed increased populations of CD3+/CD4+, CD3+/CD8+, CD14+ and CD 19+ cells. Interestingly, PSC-treated mice demonstrated significant increase in CD3+/CD4+ and CD19+ cells. Most importantly, mice treated with PSC showed improved CD4+/CD8+ ratio; which indicated potential immunostimulating activity by PSC. In addition, no physical changes and signs of mortality could be detected from PSC-treated mice. The results suggest that PSC may improve general immune status when consumed consistently as a daily food option. |
| first_indexed | 2024-03-06T14:44:37Z |
| format | Article |
| id | usm.eprints-27595 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T14:44:37Z |
| publishDate | 2014 |
| publisher | Research & Reviews |
| record_format | dspace |
| spelling | usm.eprints-275952017-08-28T05:02:46Z http://eprints.usm.my/27595/ Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. Nurul, A. A. Jonathan, M. A. Jamaruddin, M. A. Wan Rosli, W. I. RA0421 Public health. Hygiene. Preventive Medicine TP368-456 Food processing and manufacture TX341-641 Nutrition. Foods and food supply Pleurotus sajor-caju (oyster mushroom, PSC) is widely used in culinary due to its various benefits on human health. However, no study has been reported on its immunomodulating properties. Cultivated mushroom powder was used for hot aqueous extraction using Soxhlet technique. The PSC extract was suspended into CMC and prepared into 3 groups: 0.2 g/kg, 1g/kg and 2g/kg. Balb/c mice were orally fed daily for 21 consecutive days. Treatment of mice with various concentrations of PSC showed increased populations of CD3+/CD4+, CD3+/CD8+, CD14+ and CD 19+ cells. Interestingly, PSC-treated mice demonstrated significant increase in CD3+/CD4+ and CD19+ cells. Most importantly, mice treated with PSC showed improved CD4+/CD8+ ratio; which indicated potential immunostimulating activity by PSC. In addition, no physical changes and signs of mortality could be detected from PSC-treated mice. The results suggest that PSC may improve general immune status when consumed consistently as a daily food option. Research & Reviews 2014-07 Article PeerReviewed application/pdf en cc_by http://eprints.usm.my/27595/1/AA_Nurul_MUHA.pdf Nurul, A. A. and Jonathan, M. A. and Jamaruddin, M. A. and Wan Rosli, W. I. (2014) Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. Research & Reviews in Pharmacy and Pharmaceutical sciences, 3 (3). pp. 27-32. ISSN 2320-1215 https://www.rroij.com/pharmacy-and-pharmaceutical-sciences.php |
| spellingShingle | RA0421 Public health. Hygiene. Preventive Medicine TP368-456 Food processing and manufacture TX341-641 Nutrition. Foods and food supply Nurul, A. A. Jonathan, M. A. Jamaruddin, M. A. Wan Rosli, W. I. Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title | Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title_full | Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title_fullStr | Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title_full_unstemmed | Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title_short | Immunomodulatory Effects of Oyster Mushroom (Pleurotus sajor-caju) Extract In Balb/c Mice. |
| title_sort | immunomodulatory effects of oyster mushroom pleurotus sajor caju extract in balb c mice |
| topic | RA0421 Public health. Hygiene. Preventive Medicine TP368-456 Food processing and manufacture TX341-641 Nutrition. Foods and food supply |
| url | http://eprints.usm.my/27595/1/AA_Nurul_MUHA.pdf |
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