Studying the role of periplasmic chaperones in Fab presentation on phage surface.

In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen bindin...

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Main Author: Lim , Theam Soon
Format: Monograph
Published: Universiti Sains Malaysia
Subjects:
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author Lim , Theam Soon
author_facet Lim , Theam Soon
author_sort Lim , Theam Soon
collection USM
description In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen binding) fragments during phage display is largely due to the complexity of disulphide bond formation
first_indexed 2024-03-06T14:57:14Z
format Monograph
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institution Universiti Sains Malaysia
last_indexed 2024-03-06T14:57:14Z
publisher Universiti Sains Malaysia
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spelling usm.eprints-325602017-08-14T06:43:22Z http://eprints.usm.my/32560/ Studying the role of periplasmic chaperones in Fab presentation on phage surface. Lim , Theam Soon R735-854 Medical education. Medical schools. Research In phage display technology, antibodies presented on phage particles are often a smaller variant of the antibody molecule. The Fab format consists of a pair of heavy chain and light chain that is linked together via a disulphide bridge. The low presentation efficiency of Fab (fragment antigen binding) fragments during phage display is largely due to the complexity of disulphide bond formation Universiti Sains Malaysia Monograph NonPeerReviewed Lim , Theam Soon Studying the role of periplasmic chaperones in Fab presentation on phage surface. Project Report. Universiti Sains Malaysia. (Submitted)
spellingShingle R735-854 Medical education. Medical schools. Research
Lim , Theam Soon
Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title_full Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title_fullStr Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title_full_unstemmed Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title_short Studying the role of periplasmic chaperones in Fab presentation on phage surface.
title_sort studying the role of periplasmic chaperones in fab presentation on phage surface
topic R735-854 Medical education. Medical schools. Research
work_keys_str_mv AT limtheamsoon studyingtheroleofperiplasmicchaperonesinfabpresentationonphagesurface