Electrophiles and Michael acceptors as Nrf2 modulators in a Caenorhabditis elegans model.

Amyloid-beta (AI3) toxicity has been proposed and demonstrated to be a key contributor to the neurodegenerative process in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease (AD).The mechanisms by which AI3 leads to neuronal damage and dysfunction are still not well unde...

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Bibliographic Details
Main Author: Lee , Chong Yew
Format: Monograph
Published: Universiti Sains Malaysia
Subjects:

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