THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE
Anxiety is a multifaceted emotional disorder which requires multiple research models for effective assessment of the condition. Usually, a large number of animals will be used for a single study which will not be reused in other studies. The use of different groups of animals for different aspects o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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2016
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| Online Access: | http://eprints.usm.my/35782/1/Jaya_Kumar_et_al_RR_2016.pdf |
| _version_ | 1825833343592169472 |
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| author | Kumar, Jaya Hapidin, Hermizi Get Bee, Yvonne-Tee Ismail, Zalina |
| author_facet | Kumar, Jaya Hapidin, Hermizi Get Bee, Yvonne-Tee Ismail, Zalina |
| author_sort | Kumar, Jaya |
| collection | USM |
| description | Anxiety is a multifaceted emotional disorder which requires multiple research models for effective assessment of the condition. Usually, a large number of animals will be used for a single study which will not be reused in other studies. The use of different groups of animals for different aspects of any study may create inter-subject variations that can confound the observed results. Objective of this study is to investigate the effect of pre-exposure to open field (OF) on the anxiety and locomotor behaviors of male adult Wistar rats in elevated plus maze (EPM). We evaluated the effect of pre-exposure in OF on the anxiety and locomotor behaviors of rats at 3 different time intervals. The control group consisted of rats which underwent single exposure in EPM, and the other three groups consisted of rats which underwent a pre-exposure in OF immediately before the EPM session, 2 days before the EPM session, and a week before the EPM session. Our results show that there was no significant effect of OF pre-exposure on the anxiety and the locomotive behavior of rats in EPM at these 3 different intervals. In conclusions, these tests can be conducted successively with minimum time duration in the gap between these two tests. |
| first_indexed | 2024-03-06T15:06:24Z |
| format | Article |
| id | usm.eprints-35782 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:06:24Z |
| publishDate | 2016 |
| record_format | dspace |
| spelling | usm.eprints-357822017-07-21T07:48:55Z http://eprints.usm.my/35782/ THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE Kumar, Jaya Hapidin, Hermizi Get Bee, Yvonne-Tee Ismail, Zalina RA0421 Public health. Hygiene. Preventive Medicine Anxiety is a multifaceted emotional disorder which requires multiple research models for effective assessment of the condition. Usually, a large number of animals will be used for a single study which will not be reused in other studies. The use of different groups of animals for different aspects of any study may create inter-subject variations that can confound the observed results. Objective of this study is to investigate the effect of pre-exposure to open field (OF) on the anxiety and locomotor behaviors of male adult Wistar rats in elevated plus maze (EPM). We evaluated the effect of pre-exposure in OF on the anxiety and locomotor behaviors of rats at 3 different time intervals. The control group consisted of rats which underwent single exposure in EPM, and the other three groups consisted of rats which underwent a pre-exposure in OF immediately before the EPM session, 2 days before the EPM session, and a week before the EPM session. Our results show that there was no significant effect of OF pre-exposure on the anxiety and the locomotive behavior of rats in EPM at these 3 different intervals. In conclusions, these tests can be conducted successively with minimum time duration in the gap between these two tests. 2016-06 Article PeerReviewed application/pdf en http://eprints.usm.my/35782/1/Jaya_Kumar_et_al_RR_2016.pdf Kumar, Jaya and Hapidin, Hermizi and Get Bee, Yvonne-Tee and Ismail, Zalina (2016) THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE. Regenerative Research, 4 (2). pp. 11-14. ISSN 2232-0822 |
| spellingShingle | RA0421 Public health. Hygiene. Preventive Medicine Kumar, Jaya Hapidin, Hermizi Get Bee, Yvonne-Tee Ismail, Zalina THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title | THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title_full | THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title_fullStr | THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title_full_unstemmed | THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title_short | THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE |
| title_sort | effects of open field exposure on the anxiety and locomotive behavior of adult male wistar rats in elevated plus maze |
| topic | RA0421 Public health. Hygiene. Preventive Medicine |
| url | http://eprints.usm.my/35782/1/Jaya_Kumar_et_al_RR_2016.pdf |
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