A review of optic perineuritis
Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf |
| _version_ | 1825833523943047168 |
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| author | Tai , Evelyn Li Min Tevaraj, Jessica Mani Penny Thavaratnam, Lakana Kumar Mohd Noor, Raja Azmir Win Mar , Salmah Wan Hitam, Wan Hazabbah |
| author_facet | Tai , Evelyn Li Min Tevaraj, Jessica Mani Penny Thavaratnam, Lakana Kumar Mohd Noor, Raja Azmir Win Mar , Salmah Wan Hitam, Wan Hazabbah |
| author_sort | Tai , Evelyn Li Min |
| collection | USM |
| description | Optic perineuritis ( OPN ) refers to a spectrum of
conditions involving pathologic inflammation of the optic
nerve sheath. The classic triad of OPN consists of
unilateral optic neuropathy associated with pain and/or
disc oedema, but the condition often mimics other optic
neuropathies, resulting in delayed diagnosis and
suboptimal treatment. We performed a database search
of Medline and Ovid in January 2016 for articles published
in any language with the keywords ‘optic perineuritis蒺.
Sixty articles were found, published from 1956 to 2015.
Two reviewers (Tai ELM and Tevaraj JMP) performed an
independent screening of abstracts. Articles of interest
were subsequently examined. In this review, we highlight
the salient features of OPN, with particular emphasis on
the clinical differences between OPN and optic neuritis.
Although the majority of cases of OPN are idiopathic, investigations are required to rule out specific infectious
and inflammatory causes of secondary OPN. MRI is an
invaluable component of the workup, as radiographic
demonstration of peri - neural inflammation is diagnostic
of OPN. Corticosteroid therapy results in dramatic and
rapid reversal of the signs and symptoms, but prolonged
therapy with slow tapering of oral corticosteroids may be
necessary to reduce the risk of relapses. |
| first_indexed | 2024-03-06T15:09:06Z |
| format | Article |
| id | usm.eprints-36714 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:09:06Z |
| publishDate | 2017 |
| publisher | Press of International Journal of Ophthalmology |
| record_format | dspace |
| spelling | usm.eprints-367142017-09-27T00:44:54Z http://eprints.usm.my/36714/ A review of optic perineuritis Tai , Evelyn Li Min Tevaraj, Jessica Mani Penny Thavaratnam, Lakana Kumar Mohd Noor, Raja Azmir Win Mar , Salmah Wan Hitam, Wan Hazabbah RE Ophthalmology Optic perineuritis ( OPN ) refers to a spectrum of conditions involving pathologic inflammation of the optic nerve sheath. The classic triad of OPN consists of unilateral optic neuropathy associated with pain and/or disc oedema, but the condition often mimics other optic neuropathies, resulting in delayed diagnosis and suboptimal treatment. We performed a database search of Medline and Ovid in January 2016 for articles published in any language with the keywords ‘optic perineuritis蒺. Sixty articles were found, published from 1956 to 2015. Two reviewers (Tai ELM and Tevaraj JMP) performed an independent screening of abstracts. Articles of interest were subsequently examined. In this review, we highlight the salient features of OPN, with particular emphasis on the clinical differences between OPN and optic neuritis. Although the majority of cases of OPN are idiopathic, investigations are required to rule out specific infectious and inflammatory causes of secondary OPN. MRI is an invaluable component of the workup, as radiographic demonstration of peri - neural inflammation is diagnostic of OPN. Corticosteroid therapy results in dramatic and rapid reversal of the signs and symptoms, but prolonged therapy with slow tapering of oral corticosteroids may be necessary to reduce the risk of relapses. Press of International Journal of Ophthalmology 2017-02 Article PeerReviewed application/pdf en http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf Tai , Evelyn Li Min and Tevaraj, Jessica Mani Penny and Thavaratnam, Lakana Kumar and Mohd Noor, Raja Azmir and Win Mar , Salmah and Wan Hitam, Wan Hazabbah (2017) A review of optic perineuritis. International Eye Science, 17 (2). pp. 213-216. ISSN 1672-5123 http://ies.ijo.cn/cn_publish/2017/2/201702005.pdf |
| spellingShingle | RE Ophthalmology Tai , Evelyn Li Min Tevaraj, Jessica Mani Penny Thavaratnam, Lakana Kumar Mohd Noor, Raja Azmir Win Mar , Salmah Wan Hitam, Wan Hazabbah A review of optic perineuritis |
| title | A review of optic perineuritis |
| title_full | A review of optic perineuritis |
| title_fullStr | A review of optic perineuritis |
| title_full_unstemmed | A review of optic perineuritis |
| title_short | A review of optic perineuritis |
| title_sort | review of optic perineuritis |
| topic | RE Ophthalmology |
| url | http://eprints.usm.my/36714/1/%28A_review_of_optic_perineuritis%29_201702005.pdf |
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