Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent.
Gemcitabine remains the standard treatment for pancreatic cancer. although most patients acquire resistance to the therapy. Up-regulated in pancreatic cancer. SIRTI is involved in tumorigenesis and drug resistance, However the mechanism through which SIRTl regulates drug sensitivity in cancer cells...
| Main Author: | |
|---|---|
| Format: | Monograph |
| Published: |
Universiti Sains Malaysia
2016
|
| Subjects: |
| _version_ | 1825833559489773568 |
|---|---|
| author | Oon , Chern Ein |
| author_facet | Oon , Chern Ein |
| author_sort | Oon , Chern Ein |
| collection | USM |
| description | Gemcitabine remains the standard treatment for pancreatic cancer. although most patients acquire resistance to the therapy. Up-regulated in pancreatic cancer. SIRTI is involved in tumorigenesis and drug resistance, However the mechanism through which SIRTl regulates drug sensitivity in cancer cells is mainly unknown.
|
| first_indexed | 2024-03-06T15:09:38Z |
| format | Monograph |
| id | usm.eprints-36903 |
| institution | Universiti Sains Malaysia |
| last_indexed | 2024-03-06T15:09:38Z |
| publishDate | 2016 |
| publisher | Universiti Sains Malaysia |
| record_format | dspace |
| spelling | usm.eprints-369032017-10-03T08:13:41Z http://eprints.usm.my/36903/ Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. Oon , Chern Ein R735-854 Medical education. Medical schools. Research Gemcitabine remains the standard treatment for pancreatic cancer. although most patients acquire resistance to the therapy. Up-regulated in pancreatic cancer. SIRTI is involved in tumorigenesis and drug resistance, However the mechanism through which SIRTl regulates drug sensitivity in cancer cells is mainly unknown. Universiti Sains Malaysia 2016 Monograph NonPeerReviewed Oon , Chern Ein (2016) Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. Technical Report. Universiti Sains Malaysia. |
| spellingShingle | R735-854 Medical education. Medical schools. Research Oon , Chern Ein Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title | Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title_full | Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title_fullStr | Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title_full_unstemmed | Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title_short | Fundamental studies on the mechanism of action of a novel sirtuin inhibitor (BZD9L 1) in colorectal cancer cells- towards the elucidation of a novel cancer therapeutic agent. |
| title_sort | fundamental studies on the mechanism of action of a novel sirtuin inhibitor bzd9l 1 in colorectal cancer cells towards the elucidation of a novel cancer therapeutic agent |
| topic | R735-854 Medical education. Medical schools. Research |
| work_keys_str_mv | AT oonchernein fundamentalstudiesonthemechanismofactionofanovelsirtuininhibitorbzd9l1incolorectalcancercellstowardstheelucidationofanovelcancertherapeuticagent |